Huntington disease (HD) can be seen as a model neurodegenerative disorder, in that it is
caused by a single genetic mutation and is amenable to predictive genetic testing, with …

Huntington's disease (HD) results in progressive impairment of motor and cognitive function
and neuropsychiatric disturbance. There are no disease-modifying treatments available, but …

Motor slowing, forebrain white matter loss, and striatal shrinkage have been reported in
premanifest Huntington's disease (HD) prior to overt striatal neuron loss. We carried out …

Huntington disease (HD) is a fatal progressive neurodegenerative disorder for which only
symptomatic treatment is available. A better understanding of the pathology, and …

Objective To improve the characterization of asymptomatic subjects with brain magnetic
resonance imaging (MRI) abnormalities highly suggestive of multiple sclerosis (MS), a …

Magnetic resonance imaging (MRI and single‐photon emission computed tomography
(SPECT) have a considerable role in the diagnosis of the single patient with movement …

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused
by expansion of the CAG repeat in the huntingtin gene. HD is characterized clinically by …

An abundance of research shows that magnetic resonance imaging (MRI) striatal volumes
decrease long before diagnosis of Huntington's disease (HD) and closely track disease …

Huntington disease (HD) neuropathology has a devastating effect on brain structure and
consequently brain function; neuroimaging provides a means to assess these effects in …

Huntington's disease is an inherited disorder characterized by psychiatric, cognitive, and
motor symptoms due to degeneration of medium spiny neurons in the striatum. A prodromal …