In the absence of effective interventions to prevent preterm births, improved survival of
infants who are born at the biological limits of viability has relied on advances in perinatal …

Events in fetal life impact long-term health outcomes. The placenta is the first organ to form
and is the site of juxtaposition between the maternal and fetal circulations. Most diseases of …

The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10 million …

Background Preterm birth is the leading cause of child mortality globally, with many
survivors experiencing long-term adverse consequences. Preliminary evidence suggests …

Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes …

Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …

Background Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality and
is not uncommonly associated with chorioamnionitis. We recently have demonstrated that …

Pregnant women represent a high-risk population for severe/critical COVID-19 and mortality.
However, the maternal-fetal immune responses initiated by SARS-CoV-2 infection, and …

The most common early signs of sepsis in infants are fever or hypothermia, tachypnoea,
lethargy, or new parental reports of poor feeding. Consider sepsis in infants with an …

In the last decade, the microbiota, ie, combined populations of microorganisms living inside
and on the surface of the human body, has increasingly attracted attention of researchers in …