[HTML][HTML] MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

[HTML][HTML] Human papillomaviruses as infectious agents in gynecological cancers. Oncogenic properties of viral proteins

DA Haręża, JR Wilczyński, E Paradowska - International journal of …, 2022 - mdpi.com
Human papillomaviruses (HPVs), which belong to the Papillomaviridae family, constitute a
group of small nonenveloped double-stranded DNA viruses. HPV has a small genome that …

[HTML][HTML] Role of the JAK/STAT pathway in cervical cancer: its relationship with HPV E6/E7 oncoproteins

A Gutiérrez-Hoya, I Soto-Cruz - Cells, 2020 - mdpi.com
The janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling
pathway is associated with the regulation of essential cellular mechanisms, such as …

[HTML][HTML] Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis

EL Morgan, A Macdonald - PLoS pathogens, 2019 - journals.plos.org
Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer.
Although the fundamental link between HPV infection and oncogenesis is established, the …

HPV E6/E7: insights into their regulatory role and mechanism in signaling pathways in HPV-associated tumor

Q Peng, L Wang, L Zuo, S Gao, X Jiang, Y Han… - Cancer gene …, 2024 - nature.com
Human papillomavirus (HPV) is a class of envelope-free double-stranded DNA virus. HPV
infection has been strongly associated with the development of many malignancies, such as …

The role of Th17 cells in viral infections

PS Aghbash, N Hemmat, JS Nahand… - International …, 2021 - Elsevier
The present review provides an overview of recent advances regarding the function of Th17
cells and their produced cytokines in the progression of viral diseases. Viral infections alone …

[HTML][HTML] NK cell regulation in cervical cancer and strategies for immunotherapy

A Gutiérrez-Hoya, I Soto-Cruz - Cells, 2021 - mdpi.com
Cervical cancer is one of the most prevalent gynaecological malignancies worldwide and is
related to human papillomavirus (HPV) infection, viral persistence, progression, and …

Berberine and curcumin target survivin and STAT3 in gastric cancer cells and synergize actions of standard chemotherapeutic 5-fluorouracil

A Pandey, K Vishnoi, S Mahata, SC Tripathi… - Nutrition and …, 2015 - Taylor & Francis
Aberrantly expressed survivin and STAT3 signaling have emerged as major determinants of
chemoresistance in gastric cancer. We evaluated effects of potent herbal derivatives …

[HTML][HTML] JAK/STAT signaling and cervical cancer: from the cell surface to the nucleus

A Valle-Mendiola, A Gutiérrez-Hoya, I Soto-Cruz - Genes, 2023 - mdpi.com
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling
pathway constitutes a rapid signaling module from the cell surface to the nucleus, and …

[HTML][HTML] Manipulation of JAK/STAT signalling by high-risk HPVs: Potential therapeutic targets for HPV-associated malignancies

EL Morgan, A Macdonald - Viruses, 2020 - mdpi.com
Human papillomaviruses (HPVs) are small, DNA viruses that cause around 5% of all
cancers in humans, including almost all cervical cancer cases and a significant proportion of …