The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Human antimicrobial peptides and proteins

G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Membrane active peptides and their biophysical characterization

FG Avci, B Sariyar Akbulut, E Ozkirimli - Biomolecules, 2018 - mdpi.com
In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …

Computational methods and tools in antimicrobial peptide research

PGA Aronica, LM Reid, N Desai, J Li… - Journal of Chemical …, 2021 - ACS Publications
The evolution of antibiotic-resistant bacteria is an ongoing and troubling development that
has increased the number of diseases and infections that risk going untreated. There is an …

Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy

DK Mercer, MDT Torres, SS Duay, E Lovie… - Frontiers in cellular …, 2020 - frontiersin.org
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

Antimicrobial peptides in the female reproductive tract: a critical component of the mucosal immune barrier with physiological and clinical implications

VL Yarbrough, S Winkle… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND At the interface of the external environment and the mucosal surface of the
female reproductive tract (FRT) lies a first-line defense against pathogen invasion that …

Antimicrobial peptides: possible anti-infective agents

JL Narayana, JY Chen - Peptides, 2015 - Elsevier
Multidrug-resistant bacterial, fungal, viral, and parasitic infections are major health threats.
The Infectious Diseases Society of America has expressed concern on the decrease of …

Advances in sweat wearables: sample extraction, real-time biosensing, and flexible platforms

L Qiao, MR Benzigar, JA Subramony… - … applied materials & …, 2020 - ACS Publications
Wearable biosensors for sweat-based analysis are gaining wide attention due to their
potential use in personal health monitoring. Flexible wearable devices enable sweat …

Staphylococci: colonizers and pathogens of human skin

R Coates, J Moran, MJ Horsburgh - Future microbiology, 2014 - Taylor & Francis
Staphylococci are abundant bacteria of the human skin microbiome. Several species,
particularly Staphylococcus aureus and Staphylococcus epidermidis, are opportunistic …