The fact that millions of people worldwide suffer from Alzheimer's disease (AD) or
Parkinson's disease (PD), the two most prevalent neurodegenerative diseases (NDs), has …

Acute kidney injury (AKI) is associated with increased morbidity, prolonged hospitalization,
and mortality, especially in high risk patients. Phosphodiesterase 5 inhibitors (PDE5Is) …

Background The beverage obtained by fermentation of milk with kefir grains, a complex
matrix containing acid bacteria and yeasts, has been shown to have beneficial effects in …

Background MOTS-c is one of the newly identified mitochondrial-derived peptides which
play a role in regulating metabolic homeostasis. The current study aimed to investigate …

Aim Oxidative stress and the inflammatory response contribute to the progression of
cardiovascular disease. The present study aimed to investigate whether the mitochondrial …

Clinical studies have suggested a potential involvement of endothelial dysfunction and
damage in the development and severity of acute graft-versus-host disease (aGvHD) …

Impaired redox balance contributes to the cardiovascular alterations of hypertension and
activation of nuclear factor erythroid 2–related factor 2 (Nrf2) pathway may counteract these …

Background: Published clinical practice guidelines have addressed antihypertensive
therapy and sexual dysfunction (SD) in many different ways. Objective: In this systematic …

Because diabetes mellitus (DM) is a multifactorial metabolic disease, its prevention and
treatment has been a constant challenge for basic and clinical investigators focused on …

Systemic arterial hypertension is a public health problem associated with an increased risk
of cardiovascular disease. Matrix metalloproteinases (MMP) are endopeptidases that …