NKG2D is an activating receptor expressed on the surface of natural killer (NK) cells, CD8+
T cells, and subsets of CD4+ T cells, invariant NKT cells (iNKT), and γδ T cells. In humans …

Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

Natural killer (NK) cells are well recognized for their ability to provide a first line of defence
against viral pathogens and they are increasingly being implicated in immune responses …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

NKG2D (natural-killer group 2, member D) is a powerful activating receptor expressed by
natural killer (NK) cells and T cells that regulates immune responses during infection, cancer …

Cutaneous leishmaniasis exhibits a spectrum of clinical presentations dependent upon the
parasites' persistence and host immunopathologic responses. Although cytolytic CD8 T cells …

Cytomegaloviruses (CMVs) have co-evolved with their mammalian hosts for millions of
years, leading to remarkable host specificity and high infection prevalence. Macrophages …

Human cytomegalovirus (HCMV) encodes four viral Fc-gamma receptors (vFcγRs) that
counteract antibody-mediated activation in vitro, but their role in infection and pathogenesis …

Human and mouse NKG 2D ligands (NKG 2 DL s) are absent or only poorly expressed by
most normal cells but are upregulated by cell stress, hence, alerting the immune system in …

Human cytomegalovirus (HCMV) has become a paradigm for viral immune evasion due to
its unique multitude of immune-modulatory strategies. HCMV modulates the innate as well …