Versatility of Candida antarctica lipase in the amide bond formation applied in organic synthesis and biotechnological processes

RN Lima, CS dos Anjos, EVM Orozco, ALM Porto - Molecular Catalysis, 2019 - Elsevier
Lipase from Candida antarctica (CAL-A or CAL-B) can be considered the most efficient and
widely used enzyme in aminolysis and ammonolysis reactions, as well as for esterification …

Poly (amidoamine) s: Past, present, and perspectives

P Ferruti - Journal of Polymer Science Part A: Polymer …, 2013 - Wiley Online Library
Poly (amidoamine) s (PAAs) are a family of synthetic polymers obtained by stepwise
polyaddition of prim‐or sec‐amines to bisacrylamides. Nearly all conceivable …

Lipase‐catalyzed stereoselective cross‐aldol reaction promoted by water

ZB Xie, N Wang, LH Zhou, F Wan, T He, ZG Le… - …, 2013 - Wiley Online Library
PPL, lipase from porcine pancreas, is first reported to catalyze direct asymmetric aldol
reactions between aromatic aldehydes and cyclic ketones. More importantly, the catalytic …

Lipase-catalyzed aza-Michael reaction on acrylate derivatives

P Steunenberg, M Sijm, H Zuilhof… - The Journal of …, 2013 - ACS Publications
A methodology has been developed for an efficient and selective lipase-catalyzed aza-
Michael reaction of various amines (primary and secondary) with a series of acrylates and …

Trypsin-catalyzed tandem reaction: One-pot synthesis of 3, 4-dihydropyrimidin-2 (1H)-ones by in situ formed acetaldehyde

ZB Xie, N Wang, WX Wu, ZG Le, XQ Yu - Journal of biotechnology, 2014 - Elsevier
A simple, mild, one-pot tandem method catalyzed by trypsin was developed for the synthesis
of 3, 4-dihydropyrimidin-2 (1H)-ones by the Biginelli reaction of urea, β-dicarbonyl …

Bactericidal Biodegradable Linear Polyamidoamines Obtained with the Use of Endogenous Polyamines

N Śmigiel-Gac, A Smola-Dmochowska… - International Journal of …, 2024 - mdpi.com
The work presents the synthesis of a series of linear polyamidoamines by polycondensation
of sebacoyl dichloride with endogenous polyamines: putrescine, spermidine, spermine, and …

Improved Enzymatic Procedure for the Synthesis of Anandamide and N‐Fatty Acylalkanolamine Analogues: A Combination Strategy to Antitumor Activity

PG Quintana, G Garcia Linares… - European Journal of …, 2016 - Wiley Online Library
Twenty N‐fatty acylamines from linolenic and arachidonic acids, fifteen of them new
compounds, were obtained through Candida antarctica B lipase‐catalyzed esterification and …

Promiscuous Behavior of Rhizomucor miehei Lipase in the Synthesis of N‐Substituted β‐Amino Esters

LN Monsalve, F Gillanders, A Baldessari - 2012 - Wiley Online Library
A mild and efficient procedure for the aza‐Michael addition of amines to acrylates by using
lipases as catalysts is reported. Various lipases, mono‐and bifunctional amines, alkyl …

Lipases as efficient catalysts in the synthesis of monomers and polymers with biomedical applications

G Garcia Linares, A Baldessari - Current Organic Chemistry, 2013 - ingentaconnect.com
Enzymatic polymerization shows to be an advantageous approach in polymer chemistry,
particularly in the case of obtaining polymers required for biomedical applications, which are …

Different bio/Lewis acid-catalyzed stereoselective aldol reactions in various mediums

T Yıldız, H Yaşa, B Hasdemir, AS Yusufoğlu - Monatshefte für Chemie …, 2017 - Springer
In this work eight different crude biocatalysts together with six Lewis and three Brønsted
acids were used for asymmetric aldol reactions of aromatic, heteroaromatic, cyclic, and …