Novel 2-acetamido-2-ylidene-4-imidazole derivatives (El-Saghier reaction): Green synthesis, biological assessment, and molecular docking

AM El-Saghier, A Abdou, MAA Mohamed… - ACS …, 2023 - ACS Publications
El-Saghier reaction is the novel, general, and green reaction of various amines with ethyl
cyanoacetate and ethyl glycinate hydrochloride. A new series of imidazolidin-4-ones and bis …

An efficient eco-friendly, simple, and green synthesis of some new spiro-N-(4-sulfamoyl-phenyl)-1, 3, 4-thiadiazole-2-carboxamide derivatives as potential inhibitors of …

AM El-Saghier, SS Enaili, A Abdou, AM Kadry - Molecular Diversity, 2024 - Springer
Introduction The coronavirus disease 2019 (COVID-19) pandemic has caused a global
health crisis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a …

Synthesis, docking and characterization of some novel 5-(S-alkyl)-1.3. 4-thiadiazole-2-carboxamide derivatives as anti-inflammatory and antibacterial agents

AM El-Saghier, A Abdul-Baset, OM El-Hady… - BMC chemistry, 2024 - Springer
Because of the great pharmacological and industrial significance of 1, 3, 4-thiadiazole and
its related compounds, researchers are still very interested in them. For this reason, in this …