Background Malaria, caused by the parasitic protist Plasmodium falciparum, represents a
major public health problem in the developing world. The P. falciparum genome has been …

The malaria parasite is a unicellular eukaryotic organism which, during the course of its
complex life cycle, invades the red blood cells of its vertebrate host. As it grows and …

Metasurface-based sensors have emerged as an innovative technology in biosensing,
offering enhanced sensitivity and versatility across a wide range of applications. In this …

Calcium-dependent protein kinases play a crucial role in intracellular calcium signaling in
plants, some algae and protozoa. In Plasmodium falciparum, calcium-dependent protein …

* Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, São
Paulo 05508-90, Brasil† Dipartimento di Scienze Biomediche Sperimentali, Centro CNR …

Drug resistance in Plasmodium parasites is a constant threat. Novel therapeutics, especially
new drug combinations, must be identified at a faster rate. In response to the urgent need for …

Malaria parasites, Plasmodia, spend most of their asexual life cycle within red blood cells,
where they proliferate and mature. The erythrocyte cytoplasm has very low [Ca2+](< 100 …

The host hormone melatonin increases cytoplasmic Ca2+ concentration and synchronizes
Plasmodium cell cycle (Hotta, CT, ML Gazarini, FH Beraldo, FP Varotti, C. Lopes, RP …

Apicomplexan parasites rely on calcium-mediated signaling for a variety of vital functions
including protein secretion, motility, cell invasion, and differentiation. These functions are …

The acidic food vacuole exerts several important functions during intraerythrocytic
development of the human malarial parasite Plasmodium falciparum. Hemoglobin taken up …