Building thalamic neuronal networks during mouse development

I Huerga-Gómez, FJ Martini… - Frontiers in Neural …, 2023 - frontiersin.org
The thalamic nuclear complex contains excitatory projection neurons and inhibitory local
neurons, the two cell types driving the main circuits in sensory nuclei. While excitatory …

Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids

D Medina-Cano, EK Corrigan, RA Glenn… - …, 2022 - journals.biologists.com
Directed differentiation of pluripotent stem cells (PSCs) is a powerful model system for
deconstructing embryonic development. Although mice are the most advanced mammalian …

Regulation of neuronal fate specification and connectivity of the thalamic reticular nucleus by the Ascl1-Isl1 transcriptional cascade

QH Nguyen, HN Tran, Y Jeong - Cellular and Molecular Life Sciences, 2024 - Springer
The thalamic reticular nucleus (TRN) is an anatomical and functional hub that modulates the
flow of information between the cerebral cortex and thalamus, and its dysfunction has been …

FGF3 Directs the Pathfinding of Prethalamic GABAergic Axons

H Huang, Q Chen, Z Xu, F Liu - International Journal of Molecular …, 2023 - mdpi.com
The thalamus plays a crucial role in ensuring the faithful transfer of sensory information,
except olfactory signals, to corresponding cortical areas. However, thalamic function is not …

Somatotopy of Mouse Spinothalamic Innervation and the Localization of a Noxious Stimulus Requires Deleted in Colorectal Carcinoma Expression by Phox2a …

S Rastegar-Pouyani, TE Kennedy… - Journal of …, 2022 - Soc Neuroscience
Anterolateral system (AS) neurons transmit pain signals from the spinal cord to the brain.
Their morphology, anatomy, and physiological properties have been extensively …

Gli2-Mediated Shh Signaling Is Required for Thalamocortical Projection Guidance

A Callejas-Marin, JA Moreno-Bravo… - Frontiers in …, 2022 - frontiersin.org
The thalamocortical projections are part of the most important higher level processing
connections in the vertebrates and follow a highly ordered pathway from their origin in the …

[PDF][PDF] The role of FGF3 in the guidance of prethalamic GABAergic axons

H Huang, Q Chen, W Zhang, S Yu, C Zhang, Z Xu… - 2022 - scholar.archive.org
The thalamus plays a crucial role in ensuring faithful transfer of sensory information, except
olfactory signals, to corresponding cortical areas. However, thalamic function is not simply …

Pax6 regulates the morphological and electrophysiological development of mouse prethalamic neurons

T Tian, I Quintana-Urzainqui, Z Kozić, T Pratt, DJ Price - bioRxiv, 2021 - biorxiv.org
Pax6 is a well-known regulator of early neuroepithelial progenitor development. Its
constitutive loss has a particularly strong effect on the developing prethalamus, causing it to …

[图书][B] Netrin1: DCC signalling in the development of somatotopic order in the somatosensory system

S Rastegar-Pouyani - 2022 - search.proquest.com
The ability to localize noxious stimuli, also known as nociceptive topognosis, is critical for
animal survival. Anterolateral system neurons (AS), many of which are commissural, transmit …

[引用][C] Development of the thalamocortical systems

S Bandiera, Z Molnár - The Thalamus; Cambridge University Press …, 2022