The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Considerations and caveats in combating ESKAPE pathogens against nosocomial infections

YX Ma, CY Wang, YY Li, J Li, QQ Wan… - Advanced …, 2020 - Wiley Online Library
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Near infrared light-triggered on-demand Cur release from Gel-PDA@ Cur composite hydrogel for antibacterial wound healing

B Tao, C Lin, Z Yuan, Y He, M Chen, K Li, J Hu… - Chemical Engineering …, 2021 - Elsevier
The development of antibacterial and rapid hemostatic wound dressing with good
biocompatibility is urgently required for promoting non-healing wounds. In this work, a …

Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

[HTML][HTML] Poly (α-l-lysine)-based nanomaterials for versatile biomedical applications: Current advances and perspectives

M Zheng, M Pan, W Zhang, H Lin, S Wu, C Lu, S Tang… - Bioactive Materials, 2021 - Elsevier
Abstract Poly (α-l-lysine)(PLL) is a class of water-soluble, cationic biopolymer composed of α-
l-lysine structural units. The previous decade witnessed tremendous progress in the …

Polymers as advanced antibacterial and antibiofilm agents for direct and combination therapies

Z Si, W Zheng, D Prananty, J Li, CH Koh, ET Kang… - Chemical …, 2022 - pubs.rsc.org
The growing prevalence of antimicrobial drug resistance in pathogenic bacteria is a critical
threat to global health. Conventional antibiotics still play a crucial role in treating bacterial …

Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing

Y Li, M Han, Y Cai, B Jiang, Y Zhang, B Yuan… - Biomaterials …, 2022 - pubs.rsc.org
The process of wound healing is often accompanied by bacterial infection, which is a
serious threat to human health. The abuse of antibiotics in traditional therapy aggravates the …

Antimicrobial polymeric nanoparticles

SJ Lam, EHH Wong, C Boyer, GG Qiao - Progress in polymer science, 2018 - Elsevier
Currently, infections caused by multidrug-resistant bacteria have reached critical levels.
Thus, various approaches are being explored for the development of new and effective …

Synthesis, self-assembly, and biomedical applications of antimicrobial peptide–polymer conjugates

H Sun, Y Hong, Y Xi, Y Zou, J Gao, J Du - Biomacromolecules, 2018 - ACS Publications
Antimicrobial peptides (AMPs) have been attracting much attention due to their excellent
antimicrobial efficiency and low rate in driving antimicrobial resistance (AMR), which has …

Biodegradable antibacterial polymeric nanosystems: a new hope to cope with multidrug‐resistant bacteria

X Ding, A Wang, W Tong, FJ Xu - Small, 2019 - Wiley Online Library
The human society is faced with daunting threats from bacterial infections. Over decades, a
variety of antibacterial polymeric nanosystems have exhibited great promise for the …