Experimental and clinical reports on anti‐inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive …

A Memarzia, MR Khazdair, S Behrouz… - …, 2021 - Wiley Online Library
Curcuma longa (C. longa) or turmeric is a plant with a long history of use in traditional
medicine, especially for treating inflammatory conditions C. longa and its main constituent …

Recent trends in hydroxyapatite supplementation for osteoregenerative purposes

A Zastulka, S Clichici, M Tomoaia-Cotisel, A Mocanu… - Materials, 2023 - mdpi.com
Bone regeneration has gained attention in the biomedical field, which has led to the
development of materials and synthesis methods meant to improve osseointegration and …

Attenuation of oxidative stress-induced osteoblast apoptosis by curcumin is associated with preservation of mitochondrial functions and increased Akt-GSK3β …

P Dai, Y Mao, X Sun, X Li, I Muhammad, W Gu… - Cellular Physiology and …, 2017 - karger.com
Background: Osteoblast apoptosis induced by oxidative stress plays a crucial role in the
development and progression of osteoporosis. Curcumin, a natural antioxidant isolated from …

Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway

Z Chen, J Xue, T Shen, S Mu… - … journal of molecular …, 2016 - spandidos-publications.com
It is known that prolonged glucocorticoid (GC) treatment results in osteoporosis. This study
aimed to evaluate the protective effects of curcumin on the bones of rats with …

Protective effects of curcumin against osteoporosis and its molecular mechanisms: a recent review in preclinical trials

S Yang, Y Sun, L Kapilevich, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Osteoporosis (OP) is one of the most common metabolic skeletal disorders and is commonly
seen in the elderly population and postmenopausal women. It is mainly associated with …

HO-1 in bone biology: potential therapeutic strategies for osteoporosis

X Zhou, W Yuan, X Xiong, Z Zhang, J Liu… - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoporosis is a prevalent bone disorder characterized by bone mass reduction and
deterioration of bone microarchitecture leading to bone fragility and fracture risk. In recent …

Curcumin protects osteoblasts from oxidative stress-induced dysfunction via GSK3β-Nrf2 signaling pathway

X Li, Y Chen, Y Mao, P Dai, X Sun, X Zhang… - … in Bioengineering and …, 2020 - frontiersin.org
Osteoblasts dysfunction, induced by oxidative stress (OS), is one of major pathological
mechanisms for osteoporosis. Curcumin (Cur), a bioactive antioxidant compound, isolated …

Systemic administration of curcumin affect anxiety‐related behaviors in a rat model of posttraumatic stress disorder via activation of serotonergic systems

B Lee, H Lee - Evidence‐Based Complementary and …, 2018 - Wiley Online Library
Posttraumatic stress disorder (PTSD) is a trauma‐induced psychiatric disease characterized
by impaired hyperarousal, fear extermination, depression, anxiety, and amnesic symptoms …

Antiosteoporotic effect of hesperidin against ovariectomy‐induced osteoporosis in rats via reduction of oxidative stress and inflammation

Q Zhang, X Song, X Chen, R Jiang… - … of biochemical and …, 2021 - Wiley Online Library
Osteoporosis is a serious health problem, especially in geriatric patients. Worldwide, it
affects 8.9 million people every year. Oxidative stress and inflammation expand the …

[HTML][HTML] Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2 …

D Ke, H Xu, J Han, H Dai, X Wang, J Luo, Y Yu, J Xu - Biomedical journal, 2024 - Elsevier
Background Curcumin ameliorates bone loss by inhibiting osteoclastogenesis. Curcumin
inhibits RANKL-promoted autophagy in osteoclast precursors (OCPs), which mediates its …