SS Gholap - European journal of medicinal chemistry, 2016 - Elsevier
Pyrrole derivatives comprise a class of biologically active heterocyclic compounds which can serve as promising scaffolds for antimicrobial, antiviral, antimalarial, antitubercular, anti …
Diabetes is one of the major diseases worldwide and is the third leading cause of death in the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …
Diabetes mellitus occurrence has been associated to the modification of the physiological levels of glucose and is often accompanied by several long-term complications, namely …
R Maccari, R Ottanà - Journal of medicinal chemistry, 2015 - ACS Publications
Aldose reductase (AR) is an aldo–keto reductase that has been widely investigated as an enzyme crucially involved in the pathogenesis of chronic complications associated with …
A Kousaxidis, A Petrou, V Lavrentaki… - European Journal of …, 2020 - Elsevier
Diabetes mellitus is a metabolic disease characterized by high blood glucose levels and usually associated with several chronic pathologies. Aldose reductase and protein tyrosine …
An overview of pyrroles as distinct scaffolds with therapeutic potential and the significance of pyrrole derivatives for drug development are provided in this article. It lists instances of …
A Kousaxidis, L Kovacikova, I Nicolaou… - Medicinal Chemistry …, 2021 - Springer
Sepsis is a life-threatening disease that affects millions of people worldwide. Microbial infections that lead to sepsis syndrome are associated with an increased production of …
Abstract Mimosa tenuiflora (Willd.) Poiret, popularly known in Brazil as “jurema-preta” is widely used against bronchitis, fever, headache and inflammation. Its antioxidant, anti …
WI Pérez, Y Soto, C Ortíz, J Matta… - Bioorganic & medicinal …, 2015 - Elsevier
Three new ferrocene complexes were synthesized with 4-(1 H-pyrrol-1-yl) phenol group appended to one of the Cp ring. These are: 1, 1′-4-(1H-pyrrol-1-yl) phenyl …