Simulation of 3D centimeter-scale continuum tumor growth at sub-millimeter resolution via distributed computing
DA Goodin, HB Frieboes - Computers in biology and medicine, 2021 - Elsevier
Simulation of cm-scale tumor growth has generally been constrained by the computational
cost to numerically solve the associated equations, with models limited to representing mm …
cost to numerically solve the associated equations, with models limited to representing mm …
PAM: particle automata in modeling of multiscale biological systems
Serious problems with bridging multiple scales in the scope of a single numerical model
make computer simulations too demanding computationally and highly unreliable. We …
make computer simulations too demanding computationally and highly unreliable. We …
[PDF][PDF] Simulation of tumor necrosis in primary melanoma
Melanoma ulceration is an adverse prognostic finding. The tumor thickness and overgrowth
of the tumor necrotic center are the principal factors of ulcer development. We present here …
of the tumor necrotic center are the principal factors of ulcer development. We present here …
Continuous and discrete models of melanoma progression simulated in multi-GPU environment
Existing computational models of cancer evolution mostly represent very general
approaches for studying tumor dynamics in a homogeneous tissue. Here we present two …
approaches for studying tumor dynamics in a homogeneous tissue. Here we present two …
Complex automata as a novel conceptual framework for modeling biomedical phenomena
W Dzwinel - Advances in Intelligent Modelling and Simulation …, 2012 - Springer
We show that the complex automata (CxA) paradigm can serve as a robust general
framework which can be applied for developing advanced models of biological systems …
framework which can be applied for developing advanced models of biological systems …
[PDF][PDF] Growth of mixed cancer cell population: in silico the size matters
A Kłóś, P Płonka - 2020 - ruj.uj.edu.pl
Cancer heterogeneity is still underexplored and difficult to investigate. The whole network of
factors engaged in tumor growth makes clinical cases, as well as the in vivo and in vitro …
factors engaged in tumor growth makes clinical cases, as well as the in vivo and in vitro …
Interactive visualization tool for planning cancer treatment
We discuss the components and main requirements of the interactive visualization and
simulation system intended for better understanding the dynamics of solid tumor …
simulation system intended for better understanding the dynamics of solid tumor …
Development and evaluation of a modeling platform for evaluating immunotherapeutic efficacy in the tumor microenvironment.
DA Goodin - 2024 - ir.library.louisville.edu
The tumor microenvironment (TME) represents the complex outcome of numerous tumor,
stromal, and immune interactions, and whose composition can significantly affect treatment …
stromal, and immune interactions, and whose composition can significantly affect treatment …
PAM: Particle automata model in simulation of Fusarium graminearum pathogen expansion
The multi-scale nature and inherent complexity of biological systems are a great challenge
for computer modeling and classical modeling paradigms. We present a novel particle …
for computer modeling and classical modeling paradigms. We present a novel particle …