Biophysical insights into glucose-dependent transcriptional regulation by PDX1

ET Usher, SA Showalter - Journal of Biological Chemistry, 2022 - ASBMB
The pancreatic and duodenal homeobox 1 (PDX1) is a central regulator of glucose-
dependent transcription of insulin in pancreatic β cells. PDX1 transcription factor activity is …

[HTML][HTML] DUSP5 regulated by YTHDF1-mediated m6A modification promotes epithelial-mesenchymal transition and EGFR-TKI resistance via the TGF-β/Smad …

W Fan, Y Xing, S Yan, W Liu, J Ning, F Tian… - Cancer Cell …, 2024 - ncbi.nlm.nih.gov
Background Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of
cancer metastasis and drug resistance. The study aims to identify the genes that …

β2-Adrenoceptor Activation Favor Acquisition of Tumorigenic Properties in Non-Tumorigenic MCF-10A Breast Epithelial Cells

D Silva, C Quintas, J Gonçalves, P Fresco - Cells, 2024 - mdpi.com
Noradrenaline and adrenaline, and their cognate receptors, are currently accepted to
participate in cancer progression. They may also participate in cancer initiation, although …

Comprehensive network analysis of dysregulated genes revealed MNX1‐AS1/hsa‐miR‐4697‐3p/HOXB13 axis in ovarian cancer chemotherapy response

A Wu, J Liu, X Zhang, C Niu, G Shu, G Yin - Cancer Science, 2022 - Wiley Online Library
Poor chemotherapy response is the main obstacle of ovarian cancer (OC) treatment.
Platinum‐refractory and‐resistant patients are associated with a worse outcome than …

[HTML][HTML] MTA1-TJP1 interaction and its involvement in non-small cell lung cancer metastasis

W Wang, M Ma, L Li, Y Huang, G Zhao, Y Zhou… - Translational …, 2022 - Elsevier
Distant metastasis is the main cause of death in non-small cell lung cancer (NSCLC)
patients. The mechanism of metastasis-associated protein 1 (MTA1) in NSCLC has not been …

[PDF][PDF] β2-Adrenoceptor Activation Favor Acquisition of Tumorigenic Properties in Non-Tumorigenic MCF-10A Breast Epithelial Cells. Cells 2024, 13, 262

D Silva, C Quintas, J Gonçalves, P Fresco - 2024 - academia.edu
Noradrenaline and adrenaline, and their cognate receptors, are currently accepted to
participate in cancer progression. They may also participate in cancer initiation, although …

[PDF][PDF] Activation of Human Fibroblasts by Pancreatic Cancer Cell Lines

D Safina, N Lunina, M Roschina, O Staeglasova… - megajournalsofcasereports.com
The efficiency of activation of normal human dermal fibroblasts by human pancreatic
adenocarcinoma cell lines was comparatively studied. The effect of the obtained cancer …