The transforming growth factor (TGF) beta superfamily of secreted factors is comprised of
over 30 members including Activins, Nodals, Bone Morphogenetic Proteins (BMPs), and …

Vitellogenins are a family of yolk proteins that are by far the most abundant among
oviparous animals. In the model nematode Caenorhabditis elegans, the 6 vitellogenins are …

Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Background Low salinity is one of the main factors limiting the distribution and survival of
marine species. As a euryhaline species, the Pacific oyster Crassostrea gigas is considered …

Transforming Growth Factor-β (TGF-β) superfamily ligands regulate many aspects of cell
identity, function, and survival in multicellular animals. Genes encoding five TGF-β family …

Transforming growth factor β (TGF-β) and related ligands have potent effects on an
enormous diversity of biological functions in all animals examined. Because of the strong …

Studies on cell atlas in marine invertebrates provide a better understanding of cell types,
stem cell maintenance, and lineages of cell differentiation. To investigate the molecular …

Background. Optimal treatment decisions for cancer patients require reliable prognostic and
predictive information. However, this information is inadequate in many cases. Several …

Lrig1 is the founding member of the Lrig family and has been implicated in the negative
regulation of several oncogenic receptor tyrosine kinases including ErbB2. Lrig1 is …

Many guidance receptors are proteolytically cleaved by membrane-associated
metalloproteases of the ADAM family, leading to the shedding of their ectodomains …