Hyperandrogenism in polycystic ovarian syndrome and role of CYP gene variants: a review

S Ashraf, M Nabi, F Rashid, S Amin - Egyptian Journal of Medical …, 2019 - Springer
Background Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder
characterized by anovulation, hyperandrogenism, and polycystic ovarian morphology. The …

Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome

J Xing, G Qiao, X Luo, S Liu, S Chen, G Ye… - Clinical …, 2023 - portlandpress.com
Polycystic ovary syndrome (PCOS), a common reproductive endocrine disorder in women of
reproductive age, causes anovulatory infertility. Increased apoptosis of granulosa cells has …

Physical activity, rather than diet, is linked to lower insulin resistance in PCOS women—a case-control study

J Jurczewska, J Ostrowska, M Chełchowska… - Nutrients, 2023 - mdpi.com
Insulin resistance (IR) is a prominent feature of polycystic ovary syndrome (PCOS). The
importance of lifestyle interventions in the management of PCOS is strongly highlighted and …

Quantitative changes in white blood cells: correlation with the hallmarks of polycystic ovary syndrome

AH Almaeen, AA Alduraywish, M Nabi, NN Shah… - Medicina, 2022 - mdpi.com
Background and Objectives: In women of reproductive age, leukocytosis is a risk factor that
bridges low-grade chronic inflammation (metabolic inflammation), metabolic changes, and …

Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte …

SD Yousuf, MA Ganie, U Urwat, SM Andrabi… - BMC women's …, 2023 - Springer
Background Polycystic ovary syndrome (PCOS) presents clinical symptoms of menstrual
abnormalities, excessive hair growth (hirsutism), scalp hair loss, acne and infertility …

Long non-coding RNA HLA-F antisense RNA 1 inhibits the maturation of microRNA-613 in polycystic ovary syndrome to promote ovarian granulosa cell proliferation …

X Li, L Zhu, Y Luo - Bioengineered, 2022 - Taylor & Francis
ABSTRACT MicroRNA-613 (miR-613) inhibits granulosa cell proliferation, suggesting its
involvement in polycystic ovary syndrome (PCOS). We predicted that long non-coding RNA …

CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome

S Ashraf, SUA Rasool, M Nabi, MA Ganie… - Gynecological …, 2021 - Taylor & Francis
Objective Polycystic ovarian syndrome is a complex reproductive as well as
endocrinological disorder characterized by anovulatory dysfunction, androgen excess and …

Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome

G Qiao, J Xing, X Luo, C Zhang, J Yi - Endocrine, 2022 - Springer
Purpose Polycystic ovary syndrome (PCOS) is one of the most common endocrine and
metabolic disorders, posing a serious threat to the health of women. Herein, we aimed to …

[HTML][HTML] Insulin receptor substrate 1 Gly972Arg (rs1801278) polymorphism is associated with obesity and insulin resistance in Kashmiri women with polycystic ovary …

SUA Rasool, M Nabi, S Ashraf, S Amin - Genes, 2022 - mdpi.com
Background: Polycystic ovary syndrome (PCOS) is commonly associated with metabolic
abnormalities such as hyperinsulinemia, insulin resistance and obesity. The genetic variants …

Sex-specific susceptibility to type 2 diabetes mellitus and preventive effect of linalyl acetate

YK Shin, YS Hsieh, AY Han, S Kwon, P Kang, GH Seol - Life Sciences, 2020 - Elsevier
Aims Biological, psychosocial and lifestyle risk factors interact in the development of type 2
diabetes mellitus (T2DM). To date, the effects of sex, chronic stress (CS) and high-fat diet …