As endotherms, humans exposed to a compensable cold environment rely on an increase in
thermogenic rate to counteract heat lost to the environment, thereby maintaining a stable …

Cold weather can have deleterious effects on health, tolerance, and performance. This
paper will review the physiological responses and external factors that impact cold tolerance …

That adult humans possess brown fat is now accepted—but is the brown fat metabolically
active? Does human brown fat actually combust fat to release heat? In this issue of the JCI …

Indirect evidence from human studies suggests that brown adipose tissue (BAT)
thermogenesis is fueled predominantly by fatty acids hydrolyzed from intracellular …

Key points Both brown adipose tissue (BAT) and skeletal muscle activation contribute to the
metabolic response of acute cold exposure in healthy men even under minimal shivering …

Birds are endothermic homeotherms even though they lack the well-studied heat producing
brown adipose tissue (BAT), found in several clades of eutherian mammals. Earlier studies …

For thermal physiologists, calorimetry is an important methodological tool to assess human
heat balance during heat or cold exposures. A whole body direct calorimeter remains the …

Key points Muscle‐derived thermogenesis during acute cold exposure in humans consists
of a combination of cold‐induced increases in skeletal muscle proton leak and shivering …

It is the position of the American College of Sports Medicine that exercise can be performed
safely in most cold-weather environments without incurring cold-weather injuries. The key to …

The purpose of this study was to determine whether branched-chain amino acid (BCAA)
supplementation attenuates indirect indicators of muscle damage during endurance …