Signaling pathways in obesity: mechanisms and therapeutic interventions

X Wen, B Zhang, B Wu, H Xiao, Z Li, R Li… - Signal transduction and …, 2022 - nature.com
Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Role of minerals and trace elements in diabetes and insulin resistance

P Dubey, V Thakur, M Chattopadhyay - Nutrients, 2020 - mdpi.com
Minerals and trace elements are micronutrients that are essential to the human body but
present only in traceable amounts. Nonetheless, they exhibit well-defined biochemical …

New insights into boron essentiality in humans and animals

A Biţă, IR Scorei, TA Bălşeanu, MV Ciocîlteu… - International Journal of …, 2022 - mdpi.com
Boron (B) is considered a prebiotic chemical element with a role in both the origin and
evolution of life, as well as an essential micronutrient for some bacteria, plants, fungi, and …

[HTML][HTML] Effects of boron-containing compounds on cardiovascular disease risk factors–a review

I Donoiu, C Militaru, O Obleagă, JM Hunter… - Journal of Trace …, 2018 - Elsevier
Boron is considered to be a biological trace element but there is substantial and growing
support for it to be classified as an essential nutrient for animals and humans, depending on …

[HTML][HTML] Selected physiological effects of boron compounds for animals and humans. A review

M Białek, M Czauderna, KA Krajewska… - Journal of Animal and …, 2019 - jafs.com.pl
Boron is a metalloid that plays an important role in the functioning of cell membrane,
enzymatic reactions and the hormonal and mineral metabolism of animals. Boron is also …

Sodium pentaborate prevents acetaminophen-induced hepatorenal injury by suppressing oxidative stress, lipid peroxidation, apoptosis, and inflammatory cytokines in …

E Aktas Senocak, N Utlu, S Kurt, S Kucukler… - … Trace Element Research, 2024 - Springer
Abstract Acetaminophen (N-acetyl-p-aminophenol, APAP, or paracetamol) is one of the
drugs that may be damaging to the kidneys and liver when used in excess. In this context, it …

Boron-rich diet may regulate blood lipid profile and prevent obesity: A non-drug and self-controlled clinical trial

R Kuru, S Yilmaz, G Balan, BA Tuzuner, PN Tasli… - Journal of Trace …, 2019 - Elsevier
Background: Boron is an element commonly found in nature. The main boron source for
organisms is through food and drinking water. In recent years, it is suggested that the “boron …

Boron-containing compounds for prevention, diagnosis, and treatment of human metabolic disorders

CC Ri, CR Mf, S IR, SU MA - Biological trace element research, 2023 - Springer
The application of natural and synthetic boron-containing compounds (BCC) in biomedical
field is expanding. BCC have effects in the metabolism of living organisms. Some boron …

Effects of boron-containing compounds on immune responses: review and patenting trends

KS Romero-Aguilar, IM Arciniega-Martínez… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Boron-containing compounds induce effects on immune responses. Such
effects are interesting to the biomedical field for the development of therapeutic tools to …

Boron-containing compounds as labels, drugs, and theranostic agents for diabetes and its complications

MA Soriano-Ursúa, RI Cordova-Chávez… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Diabetes is a disease with a high global burden. Current strategies have failed to limit the
advancement and impact of the disease. Successful early diagnosis and treatment will …