Native chemical ligation and extended methods: mechanisms, catalysis, scope, and limitations
V Agouridas, O El Mahdi, V Diemer, M Cargoet… - Chemical …, 2019 - ACS Publications
The native chemical ligation reaction (NCL) involves reacting a C-terminal peptide thioester
with an N-terminal cysteinyl peptide to produce a native peptide bond between the two …
with an N-terminal cysteinyl peptide to produce a native peptide bond between the two …
Peptidomimetics via modifications of amino acids and peptide bonds
I Avan, CD Hall, AR Katritzky - Chemical Society Reviews, 2014 - pubs.rsc.org
Peptidomimetics represent an important field in chemistry, pharmacology and material
science as they circumvent the limitations of traditional peptides used in therapy. Self …
science as they circumvent the limitations of traditional peptides used in therapy. Self …
Metabolites from symbiotic bacteria
J Piel - Natural product reports, 2009 - pubs.rsc.org
Metabolites from symbiotic bacteria - Natural Product Reports (RSC Publishing) DOI:10.1039/B703499G
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B703499G …
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B703499G …
Culturable rare Actinomycetes: diversity, isolation and marine natural product discovery
R Subramani, W Aalbersberg - Applied microbiology and biotechnology, 2013 - Springer
Rare Actinomycetes from underexplored marine environments are targeted in drug
discovery studies due to the Actinomycetes' potentially huge resource of structurally diverse …
discovery studies due to the Actinomycetes' potentially huge resource of structurally diverse …
Monodisperse polymer capsules: tailoring size, shell thickness, and hydrophobic cargo loading via emulsion templating
The preparation of monodisperse polymer (polydopamine, PDA) capsules by a one‐step
interfacial polymerization of dopamine onto dimethyldiethoxysilane (DMDES) emulsion …
interfacial polymerization of dopamine onto dimethyldiethoxysilane (DMDES) emulsion …
Antibacterials from the sea
The ocean contains a host of macroscopic life in a great microbial soup. Unlike the terrestrial
environment, an aqueous environment provides perpetual propinquity and blurs spatial …
environment, an aqueous environment provides perpetual propinquity and blurs spatial …
PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti‐tumour activity
JFM Leal, M Martínez‐Díez… - British journal of …, 2010 - Wiley Online Library
BACKGROUND AND PURPOSE PM01183 is a new synthetic tetrahydroisoquinoline
alkaloid that is currently in phase I clinical development for the treatment of solid tumours. In …
alkaloid that is currently in phase I clinical development for the treatment of solid tumours. In …
[HTML][HTML] Marine peptides in breast cancer: Therapeutic and mechanistic understanding
Breast cancer is the most prevalent invasive form of cancer in females and posing a great
challenge for overcoming disease burden. The growth in global cancer deaths mandates the …
challenge for overcoming disease burden. The growth in global cancer deaths mandates the …
Clinical status of anti-cancer agents derived from marine sources
R Singh, M Sharma, P Joshi… - Anti-Cancer Agents in …, 2008 - ingentaconnect.com
The chemical, biological and ecological diversity of the marine ecosystem has contributed
immensely in the discovery of extremely potent compounds that have shown potent activities …
immensely in the discovery of extremely potent compounds that have shown potent activities …
[图书][B] Marine proteins and peptides: biological activities and applications
SK Kim - 2013 - books.google.com
Food proteins and bioactive peptides play a vital role in the growth and development of the
body's structural integrity and regulation, as well as having a variety of other functional …
body's structural integrity and regulation, as well as having a variety of other functional …