Aging-induced pathological alterations of the circulatory system play a critical role in
morbidity and mortality of older adults. While the importance of cellular and molecular …

Vascular remodeling is a pathological basis of various disorders. Therefore, it is necessary
to understand the occurrence, prevention, and treatment of vascular remodeling. Krüppel …

Peripheral arterial occlusive disease is a chronic pathology affecting at least 8–12 million
people in the USA, typically treated with a vein graft bypass or through the deployment of a …

Coronary artery bypass grafting (CABG) is still the most effective method for the treatment of
coronary heart disease at present. However, the restenosis of vein grafts following surgery is …

Reductionist approaches, where individual pieces of a process are examined in isolation,
have been the mainstay of biomedical research. While these methods are effective in highly …

We predicted human lower extremity vein bypass graft remodeling by hemodynamics.
Computed tomography and duplex ultrasound scans of 55 patients were performed at 1 …

Several computational models of Vein Graft Bypass (VGB) adaptation have been developed
in order to improve the surgical outcome and they all share a common property: their …

Background Uncontrolled intimal hyperplasia (IH) after autologous saphenous vein grafting
triggers a high restenosis rate; however, its association with the activation of NADPH …

Several computational models have been developed in order to improve the outcome of
Vein Graft Bypasses in response to arterial occlusions and they all share a common …

Clopidogrel inhibits platelet aggregation and has beneficial effects on patients undergoing
coronary artery bypass grafting surgery, but it is unknown whether clopidogrel inhibits the …