Time–frequency analysis of focal seizure electroencephalographic signals performed with
depth electrodes in human temporal lobe structures has revealed the occurrence at onset of …

Mesial temporal lobe epilepsy (MTLE) is the most common form of focal epilepsy and it is
characterized by seizures that are often refractory to medications. Seizures in MTLE have …

GABAA signaling is surprisingly involved in the initiation of epileptiform activity since
increased interneuron firing, presumably leading to excessive GABA release, often …

Mesial temporal lobe epilepsy (MTLE) is characterized by recurring focal seizures that arise
from limbic areas and are often refractory to pharmacological interventions. We have …

Dravet syndrome is a severe epileptic syndrome that begins during the first year of life of
otherwise healthy babies. Over the years, the seizure burden changes, and pathology …

Dimethyl sulfoxide (DMSO) is commonly used to dissolve water-insoluble drugs due to its
dipolar and aprotic properties. It also serves as a vehicle in many pharmacological studies …

Catamenial epilepsy, defined as a periodicity of seizure exacerbation during the menstrual
cycle, affects up to 70% of epileptic women. Seizures in these patients are often non …

Background: Mesial temporal lobe epilepsy (MTLE) is a prevalent form of focal epilepsy
characterized by seizures originating from the hippocampus and adjacent regions …

The K+ channel blocker 4-aminopyridine (4AP) has been extensively used to investigate the
mechanisms underlying neuronal network synchronization in both in vitro and in vivo animal …

Epilepsy is a chronic pathological brain state that is characterized by spontaneous recurrent
seizures. Mesial temporal lobe epilepsy (MTLE) is the most common form of focal epilepsy in …