The knee joint is a complex mechanical system, and computational modelling can provide
vital information for the prediction of disease progression and of the potential for therapeutic …

There is an increased interest in studying the biomechanics of the facet joints. For in silico
studies, it is therefore important to understand the level of reliability of models for outputs of …

Tissues in the intervertebral disc have a large capacity to absorb water, partially due to the
high glycosaminoglycan (GAG) content, which decreases linearly from the nucleus pulposus …

As a primary load-resisting component, annulus fibrosus (AF) maintains structural integrity of
the entire intervertebral disc. Experiments have demonstrated that permanent deformation …

Many early stage interventions for intervertebral disc degeneration are under development
involving injection of a biomaterial into the affected tissue. Due to the complex mechanical …

Finite element models are useful for investigating internal intervertebral disc (IVD)
behaviours without using disruptive experimental techniques. Simplified geometries are …

Biological tissues with a high glycosaminoglycan (GAG) content have an excellent ability to
swell by absorbing water molecules from the surrounding environment. Our recent work …

Focal defects in the annulus fibrosus (AF) of the intervertebral disc (IVD) arising from
herniation have detrimental impacts on the IVD's mechanical function. Thus, biomimetic …

Finite element models of the intervertebral disc are used to address research questions that
cannot be tested through typical experimentation. A disc model requires complex geometry …

Intervertebral discs are soft biological tissues that have an important function in
accommodating the movement of the spine during which the discs deform and act as shock …