The ability to obtain a molecular-level understanding of the chemistry that takes place at
liquid/solid interfaces is key to the development and improvement of many chemical and …

The pharmaceutical application of exogenous natural pulmonary surfactant preparations
has shown its efficiency in the therapeutical treatment of infants with Respiratory Distress …

Pulmonary surfactant is a lipid-protein complex that coats the interior of the alveoli and
enables the lungs to function properly. Upon its synthesis, lung surfactant adsorbs at the …

The interactions of molecules such as surfactants with solid interfaces are not sufficiently
understood since their study is challenging with standard spectroscopic methods. In this …

Highlights•KL 4 (sinapultide) was developed as a peptide replacement for surfactant protein
B.•Surfaxin, containing KL 4, is the first clinically approved peptide-based pulmonary …

Pulmonary surfactant protein SP-B is synthesized as a larger precursor, proSP-B. We report
that a recombinant form of human SP-B N forms a coiled coil structure at acidic pH. The …

While the discovery of antibiotics has made a huge contribution to medicine, bacteria that
are resistant to many antibiotics pose new challenges to medicine. Antimicrobial peptides …

In the present work, the hydrophobic properties of proSP-B, the precursor of pulmonary
surfactant protein SP-B, have been analyzed under different pH conditions, and the …

This chapter discusses the main spectroscopic techniques that have been developed or
adapted for the study of the chemistry of liquid/solid interfaces at the molecular level. It …

The transformation of the chemical industry towards more sustainable methods of research
and manufacturing is one of the largest undertakings of the current century. One key …