Combined diffusion‐relaxometry microstructure imaging: Current status and future prospects

PJ Slator, M Palombo, KL Miller… - Magnetic resonance …, 2021 - Wiley Online Library
Microstructure imaging seeks to noninvasively measure and map microscopic tissue
features by pairing mathematical modeling with tailored MRI protocols. This article reviews …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain

D Benjamini, D Iacono, ME Komlosh, DP Perl… - Brain, 2021 - academic.oup.com
Axonal injury is a major contributor to the clinical symptomatology in patients with traumatic
brain injury. Conventional neuroradiological tools, such as CT and MRI, are insensitive to …

Diffusion‐relaxation correlation spectroscopic imaging: a multidimensional approach for probing microstructure

D Kim, EK Doyle, JL Wisnowski… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To propose and evaluate a novel multidimensional approach for imaging subvoxel
tissue compartments called Diffusion‐Relaxation Correlation Spectroscopic Imaging. Theory …

Mapping astrogliosis in the individual human brain using multidimensional MRI

D Benjamini, DS Priemer, DP Perl, DL Brody… - Brain, 2023 - academic.oup.com
There are currently no non-invasive imaging methods available for astrogliosis assessment
or mapping in the central nervous system despite its essential role in the response to many …

Multidimensional correlation MRI

D Benjamini, PJ Basser - NMR in Biomedicine, 2020 - Wiley Online Library
Multidimensional correlation spectroscopy is emerging as a novel MRI modality that is well
suited for microstructure and microdynamic imaging studies, especially of biological …

Bi‐component T2* analysis of bound and pore bone water fractions fails at high field strengths

AC Seifert, SL Wehrli, FW Wehrli - NMR in Biomedicine, 2015 - Wiley Online Library
Osteoporosis involves the degradation of the bone's trabecular architecture, cortical thinning
and enlargement of cortical pores. Increased cortical porosity is a major cause of the …

Analysis of mcDESPOT‐and CPMG‐derived parameter estimates for two‐component nonexchanging systems

M Bouhrara, DA Reiter, H Celik… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To compare the reliability and stability of the multicomponent‐driven equilibrium
single pulse observation of T1 and T2 (mcDESPOT) and Carl‐Purcell‐Meiboom‐Gill …

Stabilization of parameter estimates from multiexponential decay through extension into higher dimensions

C Bi, K Fishbein, M Bouhrara, RG Spencer - Scientific Reports, 2022 - nature.com
Abstract Analysis of multiexponential decay has remained a topic of active research for over
200 years. This attests to the widespread importance of this problem and to the profound …

Noise estimation and reduction in magnetic resonance imaging using a new multispectral nonlocal maximum-likelihood filter

M Bouhrara, JM Bonny, BG Ashinsky… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Denoising of magnetic resonance (MR) images enhances diagnostic accuracy, the quality of
image manipulations such as registration and segmentation, and parameter estimation. The …