Gastric cancer (GC) is a highly aggressive malignancy that remains a significant contributor
to cancer-related mortality worldwide, despite a decline in incidence in recent years. Early …

Autoimmune disease results from the immune response against self-antigens, while cancer
develops when the immune system does not respond to malignant cells. Thus, for years …

Proper termination of cell-death-induced neural inflammation is the premise of tissue repair
in acute ischemic stroke (AIS). Macrophages scavenge cell corpses/debris and produce …

Polyetheretherketone (PEEK) has gained increased attention as an orthopedic implant
material in recent years. However, the adverse inflammatory and immunological reactions …

Mesenchymal stem cells (MSCs) have demonstrated potent immunomodulatory properties
that have shown promise in the treatment of autoimmune diseases, including rheumatoid …

Abstract CD4+ FOXP3+ Treg cells are central to the maintenance of self-tolerance and can
be defective in autoimmunity. In autoimmune rheumatic diseases, dysfunctional self …

Rheumatoid arthritis is an autoimmune disease characterized by synovium hyperplasia and
bone destruction. Macrophage extracellular traps are released from macrophages under …

Introduction Rheumatoid arthritis (RA) is a systemic autoimmune disease with limited
treatment success, characterized by chronic inflammation and progressive cartilage and …

Regulatory T cells (Tregs) display great promise in rheumatoid arthritis (RA) therapy.
However, their low number and differentiation rate limit their further application in the clinics …

Disease modifying antirheumatic drugs (DMARDs) have improved the prognosis of
autoimmune inflammatory arthritides but a large fraction of patients display partial or …