Hijacking homeostasis: Regulation of the tumor microenvironment by apoptosis

CD Gregory - Immunological reviews, 2023 - Wiley Online Library
Cancers are genetically driven, rogue tissues which generate dysfunctional, obdurate
organs by hijacking normal, homeostatic programs. Apoptosis is an evolutionarily conserved …

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

[HTML][HTML] Nanoparticle tracking analysis: an effective tool to characterize extracellular vesicles

G Kowkabany, Y Bao - Molecules, 2024 - mdpi.com
Extracellular vesicles (EVs) are membrane-enclosed particles that have attracted much
attention for their potential in disease diagnosis and therapy. However, the clinical …

Apoptotic extracellular vesicles derived from human umbilical vein endothelial cells promote skin repair by enhancing angiogenesis: from death to regeneration

J Liu, J Dong, X Pei - International Journal of Nanomedicine, 2024 - Taylor & Francis
Purpose The promotion of angiogenesis is an effective strategy for skin wound repair. While
the transplantation of endothelial cells has shown promise in vascularization, the underlying …

Diagnostic application of aptamers against leukemia, multiple myeloma and lymphoma: a review

S Yousefnia, M Negahdary - Journal of Drug Delivery Science and …, 2024 - Elsevier
One of the most dangerous cancers is the malignancy related to blood cells such as variety
types of leukemias, lymphomas and multiple myeloma. Early diagnosis of cancers can be …

Proteomics Profiling of Extracellular Vesicle for Identification of Potential Biomarkers in Alzheimer's Disease: A Comprehensive Review

JJ Pei, CP Palanisamy, S Jayaraman… - Ageing Research …, 2024 - Elsevier
The intricate origins and diverse symptoms of Alzheimer's disease (AD) pose significant
challenges for both diagnosis and treatment. Exosomes and microvesicles, which carry …

Immunological regulation of gut-tropic immune cells by extracellular vesicles

Y Matsuzaka, R Yashiro - Immunological Investigations, 2024 - Taylor & Francis
The remarkable diversity of lymphocytes, essential components of the immune system,
serves as an ingenious mechanism for maximizing the efficient utilization of limited host …

Functional diversity of apoptotic vesicle subpopulations from bone marrow mesenchymal stem cells in tissue regeneration

X Zhang, J Yang, S Ma, X Gao, G Wang… - Journal of …, 2024 - Wiley Online Library
Apoptosis releases numerous apoptotic vesicles that regulate processes such as cell
proliferation, immunity, and tissue regeneration and repair. Now, it has also emerged as an …

[HTML][HTML] The role of hepatocyte-derived extracellular vesicles in liver and extrahepatic diseases

S Li, F Cheng, Z Zhang, R Xu, H Shi, Y Yan - Biomedicine & …, 2024 - Elsevier
Extracellular vesicles (EVs) are vesicle-like bodies with a double membrane structure that
are released from the cell membrane or secreted by cells into the extracellular environment …

Lysine-Rich Polypeptide Modulates Forkhead Box O3 and Phosphoinositide 3-Kinase-Protein Kinase B Pathway To Induce Apoptosis in Breast Cancer

S Dhandapani, HS Choi, H Chung… - ACS Pharmacology & …, 2024 - ACS Publications
The PI3K/AKT/FOXO3 pathway is one of the most frequently involved signaling pathways in
cancer, including breast cancer. Therefore, we synthesized a novel lysine-rich polypeptide …