[PDF][PDF] Emerging immunotherapy for HCC: A guide for hepatologists

F Foerster, SJ Gairing, SI Ilyas, PR Galle - Hepatology, 2022 - Wiley Online Library
HCC is one of the most common cancers worldwide, and the third leading cause of cancer‐
related death globally. HCC comprises nearly 90% of all cases of primary liver cancer …

Managing the immune microenvironment of osteosarcoma: the outlook for osteosarcoma treatment

H Tian, J Cao, B Li, EC Nice, H Mao, Y Zhang… - Bone Research, 2023 - nature.com
Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Transarterial chemoembolization with PD-(L) 1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001)

HD Zhu, HL Li, MS Huang, WZ Yang, GW Yin… - Signal transduction and …, 2023 - nature.com
There is considerable potential for integrating transarterial chemoembolization (TACE),
programmed death-(ligand) 1 (PD-[L] 1) inhibitors, and molecular targeted treatments (MTT) …

[HTML][HTML] Integrated use of PD-1 inhibition and transarterial chemoembolization for hepatocellular carcinoma: evaluation of safety and efficacy in a retrospective …

B Marinelli, E Kim, A D'Alessio, M Cedillo… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICIs) have revolutionized treatment of advanced
hepatocellular carcinoma. Integrated use of transarterial chemoembolization (TACE), a …

Immunogenic cell death: an emerging target in gastrointestinal cancers

M Chiaravalli, A Spring, A Agostini, G Piro, C Carbone… - Cells, 2022 - mdpi.com
Immunogenic cell death (ICD) is a regulated form of cell death that induces the activation of
both innate and adaptive immune responses through the release of damage-associated …

[HTML][HTML] Stereotactic body radiation therapy for hepatocellular carcinoma: From infancy to ongoing maturity

S Lewis, L Dawson, A Barry, T Stanescu, I Mohamad… - JHEP Reports, 2022 - Elsevier
Hepatocellular carcinoma (HCC) accounts for 90% of liver tumours and is one of the leading
causes of mortality. Cirrhosis due to viral hepatitis, alcohol or steatohepatitis is the major risk …

Real-world efficacy and safety of TACE plus camrelizumab and apatinib in patients with HCC (CHANCE2211): a propensity score matching study

ZC Jin, BY Zhong, JJ Chen, HD Zhu, JH Sun… - European …, 2023 - Springer
Objectives This study aimed to investigate the efficacy and safety of transarterial
chemoembolization (TACE) plus camrelizumab, a monoclonal antibody targeting …

Type 2 diabetes mellitus and efficacy outcomes from immune checkpoint blockade in patients with cancer

A Cortellini, A D'Alessio, S Cleary, S Buti… - Clinical Cancer …, 2023 - AACR
Purpose: No evidence exists as to whether type 2 diabetes mellitus (T2DM) impairs clinical
outcome from immune checkpoint inhibitors (ICI) in patients with solid tumors. Experimental …

The synergistic effect of interventional locoregional treatments and immunotherapy for the treatment of hepatocellular carcinoma

N Brandi, M Renzulli - International Journal of Molecular Sciences, 2023 - mdpi.com
Immunotherapy has remarkably revolutionized the management of advanced HCC and
prompted clinical trials, with therapeutic agents being used to selectively target immune cells …

[HTML][HTML] Regulatory T cells and their associated factors in hepatocellular carcinoma development and therapy

CY Zhang, S Liu, M Yang - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Liver cancer is the third leading cause of cancer-related death worldwide with primary type
hepatocellular carcinoma (HCC). Factors, including carcinogens, infection of hepatitis …