Cognitive impairment is a frequent and meaningful symptom in multiple sclerosis (MS),
caused by the accrual of brain structural damage only partially counteracted by effective …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by
multi-systemic involvement. Nervous system involvement in SLE leads to a series of …

Objectives Cortical demyelination is common in multiple sclerosis (MS) and can be
extensive. Cortical lesions contribute to disability independently from white matter lesions …

Background Cognitive impairment is frequent and disabling in multiple sclerosis (MS).
Changes in information processing speed constitute the most important cognitive deficit in …

Cortical myelin loss and repair in multiple sclerosis (MS) have been explored in
neuropathological studies, but the impact of these processes on neurodegeneration and the …

Magnetic resonance imaging has been crucial in the development of anti-inflammatory
disease-modifying treatments. The current landscape of multiple sclerosis clinical trials is …

Background: Dramatic improvements in visualization of cortical (especially subpial) multiple
sclerosis (MS) lesions allow assessment of impact on clinical course. Objective …

Although white matter lesion number and volume still remains the imaging metric used in
daily clinical practice, further development of advanced imaging predictors of long-term …

Background: Anemia and red cell distribution width (RDW) have been linked to poor
cognitive performance, pending studies of underlying mechanisms. Objective: We examined …

Background: Cortical demyelination is a relevant aspect of tissue damage in multiple
sclerosis (MS). Microstructural changes may affect each layer in the cortex differently …