Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …

Thrombocytopenia, which signifies a low platelet count usually below 150× 109/L, is a
common finding following or during many viral infections. In clinical medicine, mild …

Background Dengue infections are on the rise in Sri Lanka and are spreading to all areas in
the country. Here, we discuss the changes in dengue epidemiology in Sri Lanka in relation …

Dengue is the most rapidly emerging mosquito-borne infection and, due to climate change
and unplanned urbanization, it is predicted that the global burden of dengue will rise further …

Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild
self-limiting illness in the majority of individuals. There is emerging evidence that an …

Background Identification of pleural effusion (PE) in dengue infection is an objective
measure of plasma leakage and may predict disease progression. However, no studies …

Severe pneumonia and multiorgan dysfunction in COVID-19 and dengue haemorrhagic
fever (DHF) are two diseases that can associate with an altered immune response to the …

Dengue is the most rapidly emerging climate-sensitive infection, and morbidity/mortality and
disease incidence are rising markedly, leading to healthcare systems being overwhelmed …

Background Activated platelets release cytokines/proteins including CXCL4 (PF4), CCL5
and fibrinopeptides, which regulate infection of several pathogenic viruses such as HIV …

Background Rupatadine was previously shown to reduce endothelial dysfunction in vitro,
reduced vascular leak in dengue mouse models and to reduce the extent of pleural …