Bisphenol A (BPA) is a widely studied typical endocrine-disrupting chemical, and one of the
major new issues is the safe replacement of this commonly used compound. Bisphenol S …

Fetal testis is a major target of endocrine disruptors (EDs). During the last 20 years, we have
developed an organotypic culture system that maintains the function of the different fetal …

BACKGROUND Metformin is a drug used in the treatment of diabetes and of some disorders
related to insulin resistance, such as polycystic ovary syndrome. Gestational diabetes can …

Endocrine disruptors (ED) have been incriminated in the current increase of male
reproductive alterations. Bisphenol A (BPA) is a widely used weak estrogenic environmental …

The endometrium becomes receptive to the embryo only in the mid-luteal phase, but not in
the other stages of the menstrual cycle. Endometrial factors play an important role in …

Background Cadmium (Cd) is a common environmental pollutant and a major constituent of
tobacco smoke. Adverse effects of this heavy metal on reproductive function have been …

Metformin is an oral anti-hyperglycemic drug that acts as an insulin sensitizer in the
treatment of diabetes mellitus type 2. It has also been widely used in the treatment of …

Background Using an organotypic culture system termed human Fetal Testis Assay (hFeTA)
we previously showed that 0.01 μM BPA decreases basal, but not LH-stimulated …

Human fetal gonads acquire endocrine steroidogenic capabilities early during their
differentiation. Genetic studies show that this endocrine function plays a central role in the …

The present study was conducted to determine whether exposure to the mono-(2-ethylhexyl)
phthalate (MEHP) represents a genuine threat to male human reproductive function. To this …