Tissue clearing and imaging methods for cardiovascular development

H Kolesová, V Olejníčková, A Kvasilová… - Iscience, 2021 - cell.com
Tissue imaging in 3D using visible light is limited and various clearing techniques were
developed to increase imaging depth, but none provides universal solution for all tissues at …

G9a promotes immune suppression by targeting the Fbxw7/Notch pathway in glioma stem cells

Y Cao, B Liu, L Cai, Y Li, Y Huang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aim Immunotherapy for glioblastoma multiforme (GBM) is limited because of a strongly
immunosuppressive tumor microenvironment (TME). Remodeling the immune TME is an …

Making sense of scattering: Seeing microstructure through shear waves

G Annio, S Holm, G Mangin, J Penney, R Bacquët… - Science …, 2024 - science.org
The physics of shear waves traveling through matter carries fundamental insights into its
structure, for instance, quantifying stiffness for disease characterization. However, the origin …

A Cellular Ground Truth to Develop MRI Signatures in Glioma Models by Correlative Light Sheet Microscopy and Atlas-Based Coregistration

K Schregel, L Heinz, J Hunger, C Pan… - Journal of …, 2023 - Soc Neuroscience
Glioblastoma is the most common malignant primary brain tumor with poor overall survival.
Magnetic resonance imaging (MRI) is the main imaging modality for glioblastoma but has …

Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time

J Almagro, HA Messal - Frontiers in Immunology, 2023 - frontiersin.org
Volume imaging visualizes the three-dimensional (3D) complexity of tumors to unravel the
dynamic crosstalk between cancer cells and the heterogeneous landscape of the tumor …

Whole brain vessel graphs: A dataset and benchmark for graph learning and neuroscience

JC Paetzold, J McGinnis, S Shit, I Ezhov… - Thirty-fifth Conference …, 2021 - openreview.net
Biological neural networks define the brain function and intelligence of humans and other
mammals, and form ultra-large, spatial, structured graphs. Their neuronal organization is …

LncRNA LINC01018/miR‐942‐5p/KNG1 axis regulates the malignant development of glioma in vitro and in vivo

J Xu, J Wang, M Zhao, C Li, S Hong… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Since the inhibitory effect of KNG1 on glioma has been proved, this study further
explores the regulation of the lncRNA/miRNA axis on KNG1 in glioma. Methods The …

Genome‐wide DNA methylation analysis identifies potent CpG signature for temzolomide response in non‐G‐CIMP glioblastomas with unmethylated MGMT promoter: MGMT …

BB Liang, YH Wang, JJ Huang, S Lin… - CNS Neuroscience …, 2024 - Wiley Online Library
Purposes To identify potent DNA methylation candidates that could predict response to
temozolomide (TMZ) in glioblastomas (GBMs) that do not have glioma‐CpGs island …

Marsdenia tenacissima extract prevents the malignant progression of glioma through upregulating lncRNA MEG3 and SFRP1‐dependent inhibition of Wnt/β‐catenin …

L Chen, X Gong, M Huang - CNS Neuroscience & Therapeutics, 2023 - Wiley Online Library
Abstract Background/Aim Recent studies have highlighted the tumor‐suppressive effect of
Marsdenia tenacissima extract (MTE) on human cancers. This research unveils the potential …

Vascular Development of Fetal and Postnatal Neocortex of the Pig, the European Wild Boar Sus scrofa

E Sobierajski, K Czubay, C Beemelmans… - Journal of …, 2024 - Wiley Online Library
The development of the brain's vascular system is a predominantly prenatal process in
mammalian species and is required for neurogenesis and further brain development. Our …