[HTML][HTML] The association of increased pre-and postnatal NO2 and PM2. 5 exposure with the infant nasal microbiome composition and respiratory symptoms

N Künstle, O Gorlanova, C Rüttimann, N Mostacci… - Environmental …, 2025 - Elsevier
Background Little is known about the mediating role of nasal microbiome on the association
between pre-and postnatal air pollution exposure and subsequent respiratory morbidity in …

Differences in autophagy marker levels at birth in preterm vs. term infants

N Künstle, O Gorlanova, A Marten, L Müller… - Pediatric …, 2024 - nature.com
Background Preterm infants are susceptible to oxidative stress and prone to respiratory
diseases. Autophagy is an important defense mechanism against oxidative-stress-induced …

Paediatric Personalized Research Network Switzerland (SwissPedHealth): a joint paediatric national data stream

R Mozun, FN Belle, A Agostini, MR Baumgartner… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Children represent a large and vulnerable patient group. However, the
evidence base for most paediatric diagnostic and therapeutic procedures remains limited or …

Sulfur hexafluoride multiple breath washin and washout outcomes in infants are not interchangeable

AC Kentgens, F Wyler, MA Oestreich… - Physiological …, 2024 - iopscience.iop.org
Objective. Sulfur hexafluoride (SF 6) multiple-breath washout (MBW) assesses ventilation
inhomogeneity, as an early marker of obstructive respiratory diseases. Primary outcomes …

Optimized algorithm for speed‐of‐sound‐based infant sulfur hexafluoride multiple‐breath washout measurements

F Wyler, T Manogaran, N Monney, Y Salem… - Pediatric …, 2024 - Wiley Online Library
Introduction Major methodological issues with the existing algorithm (WBreath) used for the
analysis of speed‐of‐sound‐based infant sulfur hexafluoride (SF6) multiple‐breath washout …

A computerized tool for the systematic visual quality assessment of infant multiple-breath washout measurements

MA Oestreich, I Doswald, Y Salem, N Künstle… - Frontiers in …, 2024 - frontiersin.org
Background Multiple-breath washout (MBW) is a sensitive method for assessing lung
volumes and ventilation inhomogeneity in infants, but remains prone to artefacts (eg, sighs) …

[引用][C] Lung function trajectories and determinants in early life

S Yammine, P Latzin - The Lancet Child & Adolescent Health, 2024 - thelancet.com
Evidence has accumulated to support the importance of early-life events on long-term lung
growth and development with consequences for overall health across the life course …