Nanomedicine fight against antibacterial resistance: an overview of the recent pharmaceutical innovations

NE Eleraky, A Allam, SB Hassan, MM Omar - Pharmaceutics, 2020 - mdpi.com
Based on the recent reports of World Health Organization, increased antibiotic resistance
prevalence among bacteria represents the greatest challenge to human health. In addition …

Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

[HTML][HTML] Biofunctional chitosan–biopolymer composites for biomedical applications

Y Guo, D Qiao, S Zhao, P Liu, F Xie, B Zhang - Materials Science and …, 2024 - Elsevier
In light of escalating biomedical demands across diverse diseases, there arises a pressing
need for the development of sophisticated biocompatible materials exhibiting augmented …

Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Insight on updates in polysaccharides for ocular drug delivery

NS Chandra, S Gorantla, S Priya, G Singhvi - Carbohydrate Polymers, 2022 - Elsevier
Ocular drug delivery is a significantly challenging task due to the presence of various
anatomical and physiological barriers in the eye. Naturally available polysaccharides, when …

Chitosan-based in situ gels for ocular delivery of therapeutics: a state-of-the-art review

T Irimia, CE Dinu-Pîrvu, MV Ghica, D Lupuleasa… - Marine drugs, 2018 - mdpi.com
Ocular in situ gels are a promising alternative to overcome drawbacks of conventional eye
drops because they associate the advantages of solutions such as accuracy and …

Chitosan Nanoparticles Inactivate Alfalfa Mosaic Virus Replication and Boost Innate Immunity in Nicotiana glutinosa Plants

A Abdelkhalek, SH Qari, MAAR Abu-Saied, AM Khalil… - Plants, 2021 - mdpi.com
Plant viral infection is one of the most severe issues in food security globally, resulting in
considerable crop production losses. Chitosan is a well-known biocontrol agent against a …

Dextran sulfate nanocarriers: design, strategies and biomedical applications

S Ramasundaram, G Saravanakumar, S Sobha… - International journal of …, 2022 - mdpi.com
Dextran sulfate (DXS) is a hydrophilic, non-toxic, biodegradable, biocompatible and safe
biopolymer. These biomedically relevant characteristics make DXS a promising building …

Absorption enhancement strategies in chitosan-based nanosystems and hydrogels intended for ocular delivery: Latest advances for optimization of drug permeation

I Dmour - Carbohydrate Polymers, 2024 - Elsevier
Ophthalmic diseases can be presented as acute diseases like allergies, ocular infections,
etc., or chronic ones that can be manifested as a result of systemic disorders, like diabetes …

Reactive oxygen species-scavenging hollow MnO 2 nanozymes as carriers to deliver budesonide for synergistic inflammatory bowel disease therapy

H Qiu, H Gong, Y Bao, H Jiang, W Tong - Biomaterials Science, 2022 - pubs.rsc.org
Inflammatory bowel disease (IBD) is related to excessive reactive oxygen species (ROS)
and high expression of proinflammatory cytokines. An enzymatically active drug carrier that …