Endocytosis is critical for many functions in eukaryotic cells. Uptake of host cell cytosol, an
indispensable endocytic process in malaria blood-stage parasites, has been known for a …

To best understand parasite, host, and vector morphologies, host–parasite interactions, and
to develop new drug and vaccine targets, structural data should, ideally, be obtained and …

New techniques for obtaining electron microscopy data through the cell volume are being
increasingly utilized to answer cell biologic questions. Here, we present a three-dimensional …

Plasmodium parasites contribute to one of the highest global infectious disease burdens. To
achieve this success, the parasite has evolved a range of specialized subcellular …

824-Pos Surface Area-to-Volume Ratio, not Cellular Viscoelasticity is the Major Determinant
of Red Blood Cell Traversal through Small Channels Arman Namvar1, 2, Adam Blanch2 …

A critical step in how malaria parasites invade red blood cells (RBCs) is the wrapping of the
membrane around the egg-shaped merozoites. Recent experiments have revealed that …

Plasmodium knowlesi is endemic across Southeast Asia, and is the commonest cause of
zoonotic malaria. The spectrum of clinical disease from P. knowlesi infection ranges from …

Malaria, which is caused by Plasmodium parasites through Anopheles mosquito
transmission, remains one of the most life-threatening diseases affecting hundreds of …

The structural integrity of the host red blood cell (RBC) is crucial for propagation of
Plasmodium spp. during the disease-causing blood stage of malaria infection. To assess the …

Despite the enormous significance of malaria parasites for global health, some basic
features of their ultrastructure remain obscure. Here, we apply high-resolution volumetric …