Mitochondrial dysfunction in aging

Y Guo, T Guan, K Shafiq, Q Yu, X Jiao, D Na… - Ageing Research …, 2023 - Elsevier
Aging is a complex process that features a functional decline in many organelles. Although
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …

Mechanisms and regulation of protein synthesis in mitochondria

E Kummer, N Ban - Nature Reviews Molecular Cell Biology, 2021 - nature.com
Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

Plant mitochondria–past, present and future

IM Møller, AG Rasmusson, O Van Aken - The Plant Journal, 2021 - Wiley Online Library
The study of plant mitochondria started in earnest around 1950 with the first isolations of
mitochondria from animal and plant tissues. The first 35 years were spent establishing the …

How to build a ribosome from RNA fragments in Chlamydomonas mitochondria

F Waltz, T Salinas-Giegé, R Englmeier… - Nature …, 2021 - nature.com
Mitochondria are the powerhouse of eukaryotic cells. They possess their own gene
expression machineries where highly divergent and specialized ribosomes, named …

Mitochondrial redox systems as central hubs in plant metabolism and signaling

O Van Aken - Plant Physiology, 2021 - academic.oup.com
Plant mitochondria are indispensable for plant metabolism and are tightly integrated into
cellular homeostasis. This review provides an update on the latest research concerning the …

Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis

H Soufari, F Waltz, C Parrot… - Proceedings of the …, 2020 - National Acad Sciences
Kinetoplastids are unicellular eukaryotic parasites responsible for such human pathologies
as Chagas disease, sleeping sickness, and leishmaniasis. They have a single large …

Assembly and analysis of the first complete mitochondrial genome of Punica granatum and the gene transfer from chloroplast genome

G Lu, K Zhang, Y Que, Y Li - Frontiers in Plant Science, 2023 - frontiersin.org
Pomegranate (Punica granatum L.) is one of the oldest fruits with edible, medicinal and
ornamental values. However, there is no report on the mitochondrial genome of …

Widespread use of unconventional targeting signals in mitochondrial ribosome proteins

YS Bykov, T Flohr, F Boos, N Zung, JM Herrmann… - The EMBO …, 2022 - embopress.org
Mitochondrial ribosomes are complex molecular machines indispensable for respiration.
Their assembly involves the import of several dozens of mitochondrial ribosomal proteins …

Mitochondrial genome insights into the spatio-temporal distribution and genetic diversity of Dendrobium hancockii Rolfe (Orchidaceae)

Z Hou, M Wang, Y Jiang, Q Xue, W Liu, Z Niu… - Frontiers in Plant …, 2024 - frontiersin.org
Introduction With its distinctive evolutionary rate and inheritance patterns separate from the
nuclear genome, mitochondrial genome analysis has become a prominent focus of current …

Miniature RNAs are embedded in an exceptionally protein-rich mitoribosome via an elaborate assembly pathway

M Valach, C Benz, LC Aguilar, O Gahura… - Nucleic Acids …, 2023 - academic.oup.com
The mitochondrial ribosome (mitoribosome) has diverged drastically from its evolutionary
progenitor, the bacterial ribosome. Structural and compositional diversity is particularly …