Background Immune checkpoint blockade (ICB) has been approved for the treatment of
triple-negative breast cancer (TNBC), since it significantly improved the progression-free …

Background. There is limited knowledge about the role of cancer‐associated fibroblasts
(CAF) in the tumor microenvironment of triple‐negative breast cancer (TNBC). Methods …

Background: Adenomatous polyposis coli (APC) gene, an oncogene, has been implicated in
stomach adenocarcinoma (STAD), which is a common type of gastric cancer (GC). Although …

Data on prevalence of programmed death ligand-1 (PD-L1) expression and its correlation
with tumor biomarkers in Chinese patients with muscle-invasive urothelial bladder cancer …

Background. Bladder cancer (BLCA) is one of the most common cancers and ranks ninth
among all cancers. Extracellular matrix (ECM) genes activate a number of pathways that …

Background: Tongue squamous cell carcinoma (TSCC) patients with high-grade tumors
usually suffer from high occurrence and poor prognosis. The current study aimed at finding …

Background: Genomic alteration is the basis of occurrence and development of carcinoma.
Specific gene mutation may be associated with the prognosis of hepatocellular carcinoma …

Background Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell
carcinoma (RCC). Immunotherapy, especially anti-PD-1, is becoming a pillar of ccRCC …

ABSTRACT Background: Immunotherapies including PD-1/PD-L1 antibodies have been
approved for the treatment of Muscle-invasive Bladder Cancer (MIBC) patients. However …

An innate immune defect is a defect in the innate immune response that reduces the
response to infection, this can occurs in genes important for activation regulation and …