[HTML][HTML] Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients
S Marie, KL Frost, RK Hau, L Martinez-Guerrero… - … Pharmaceutica Sinica B, 2023 - Elsevier
The liver plays a central role in the pharmacokinetics of drugs through drug metabolizing
enzymes and transporters. Non-alcoholic steatohepatitis (NASH) causes disease-specific …
enzymes and transporters. Non-alcoholic steatohepatitis (NASH) causes disease-specific …
Mechanisms of Intestinal Pharmacokinetic Natural Product-drug Interactions
VO Oyanna, JD Clarke - Drug Metabolism Reviews, 2024 - Taylor & Francis
The growing co-consumption of botanical natural products with conventional medications
has intensified the need to understand potentialeffects on drug safety and efficacy. This …
has intensified the need to understand potentialeffects on drug safety and efficacy. This …
Rifampin-and silymarin-mediated pharmacokinetic interactions of exogenous and endogenous substrates in a transgenic OATP1b mouse model
BJ Bechtold, KD Lynch, VO Oyanna… - Molecular …, 2024 - ACS Publications
Organic anion-transporting polypeptides (OATP) 1B1 and OATP1B3, encoded by the SLCO
gene family of the solute carrier superfamily, are involved in the disposition of many …
gene family of the solute carrier superfamily, are involved in the disposition of many …
[HTML][HTML] One-step sustainable extraction of Silymarin compounds of wild Algerian milk thistle (Silybum marianum) seeds using Gas Expanded Liquids
This work reports the application of Gas Expanded Liquid (GXL) extraction to concentrate
the flavonolignan fraction (silymarin) and taxifolin from Silybum marianum seeds, which …
the flavonolignan fraction (silymarin) and taxifolin from Silybum marianum seeds, which …
Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice
BJ Bechtold, KD Lynch, VO Oyanna, MR Call… - Drug Metabolism and …, 2024 - ASPET
Organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 (collectively, OATP1B)
transporters encoded by the solute carrier organic anion transporter (SLCO) genes mediate …
transporters encoded by the solute carrier organic anion transporter (SLCO) genes mediate …
[HTML][HTML] Silymarin for treatment of adults with nonalcoholic fatty liver disease
C Wang, G Kanaan, Y Shang, L Chai… - … Cochrane Database of …, 2023 - ncbi.nlm.nih.gov
Silymarin for treatment of adults with nonalcoholic fatty liver disease - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …
[HTML][HTML] The role of organic anion transport protein 1a4 in drug delivery and diseases: a review
D TAN, J WANG, Q ZHANG, L Qin… - Food Science and …, 2023 - SciELO Brasil
OATP1A4 is an important member of the family of organic anion transporting polypeptides
(OATPs), which is generally thought to mediate cellular uptake of endogenous and …
(OATPs), which is generally thought to mediate cellular uptake of endogenous and …
Other beneficial effects of silymarin
A Surai, PF Surai - brill.com
In this chapter additional protective effects of silymarin (SM) are described including
amatoxincontaining mushrooms poisoning, burn recovery, anti-aging effects, effects on …
amatoxincontaining mushrooms poisoning, burn recovery, anti-aging effects, effects on …