Influence of geometry on the drug release profiles of stereolithographic (SLA) 3D-printed tablets

PR Martinez, A Goyanes, AW Basit, S Gaisford - AAPS PharmSciTech, 2018 - Springer
Additive manufacturing (3D printing) permits the fabrication of tablets in shapes unattainable
by powder compaction, and so the effects of geometry on drug release behavior is easily …

3D-Printing with precise layer-wise dose adjustments for paediatric use via pressure-assisted microsyringe printing

I El Aita, J Rahman, J Breitkreutz… - European Journal of …, 2020 - Elsevier
The establishment of 3D-printing as manufacturing process for oral solid dosage forms
enables new options for the individualized medicine. The aim of this work was to develop a …

Extrusion 3D printing of paracetamol tablets from a single formulation with tunable release profiles through control of tablet geometry

SA Khaled, MR Alexander, DJ Irvine, RD Wildman… - Aaps Pharmscitech, 2018 - Springer
An extrusion-based 3D printer was used to fabricate paracetamol tablets with different
geometries (mesh, ring and solid) from a single paste-based formulation formed from …

Predicting drug release from 3D printed oral medicines based on the surface area to volume ratio of tablet geometry

H Windolf, R Chamberlain, J Quodbach - Pharmaceutics, 2021 - mdpi.com
3D printing offers the advantage of being able to modify dosage form geometry, which can
be exploited to modify release characteristics. In this study, we investigated the influence of …

Development of sustained-release drug-loaded intravesical inserts via semi-solid micro-extrusion 3D-printing for bladder targeting

J Rahman-Yildir, B Fischer, J Breitkreutz - International Journal of …, 2022 - Elsevier
Discontinued treatment and non-adherence are oftentimes weaknesses of common first-line
drug therapy against bladder conditions due to their negative side-effects. To overcome …

Budding multi-matrix technology—a retrospective approach, deep insights, and future perspectives

A Sriram, S Tangirala, S Atmakuri, S Hoque… - AAPS …, 2021 - Springer
The human race is consistently striving for achieving good health and eliminate disease-
causing factors. For the last few decades, scientists have been endeavoring to invent and …

The Influence of Shape Parameters on Unidirectional Drug Release from 3D Printed Implants and Prediction of Release from Implants with Individualized Shapes

V Domsta, C Hänsch, S Lenz, Z Gao, F Matin-Mann… - Pharmaceutics, 2023 - mdpi.com
The local treatment of diseases by drug-eluting implants is a promising tool to enable
successful therapy under potentially reduced systemic side effects. Especially, the highly …

[HTML][HTML] Selective laser sintering for printing bilayer tablets

LA Junqueira, AG Tabriz, V Garg, SS Kolipaka… - International Journal of …, 2025 - Elsevier
Abstract In this study Selective Laser Sintering (SLS) was used to produce bilayer tablets
containing rosuvastatin and acetylsalicylic acid. Initially, monolithic tablets of each drug were …

Geometry-Driven Fabrication of Mini-Tablets via 3D Printing: Correlating Release Kinetics with Polyhedral Shapes

YJ Kim, YR Choi, JH Kang, YS Park, DW Kim, CW Park - Pharmaceutics, 2024 - mdpi.com
The aim of this study was to fabricate mini-tablets of polyhedrons containing theophylline
using a fused deposition modeling (FDM) 3D printer, and to evaluate the correlation …

Development and In Vitro-In Vivo Evaluation of a Novel Sustained-Release tablet based on constant-release surface

L Wang, T Duan, Y Gao, H Liu, R Sun, T Wu… - Journal of Drug Delivery …, 2025 - Elsevier
Subject The release rate of hydrophilic gel tablets varies depending on their surface area. In
this study, we aimed to develop a sustained-release tablet that maintains a constant release …