Point of care diagnostics in resource-limited settings: A review of the present and future of PoC in its most needed environment

B Heidt, WF Siqueira, K Eersels, H Diliën… - Biosensors, 2020 - mdpi.com
Point of care (PoC) diagnostics are at the focus of government initiatives, NGOs and
fundamental research alike. In high-income countries, the hope is to streamline the …

Point-of-care HIV viral load testing: an essential tool for a sustainable global HIV/AIDS response

PK Drain, J Dorward, A Bender, L Lillis… - Clinical microbiology …, 2019 - Am Soc Microbiol
The global public health community has set ambitious treatment targets to end the HIV/AIDS
pandemic. With the notable absence of a cure, the goal of HIV treatment is to achieve …

Scale-up of routine viral load testing in resource-poor settings: current and future implementation challenges

T Roberts, J Cohn, K Bonner… - Clinical Infectious …, 2016 - academic.oup.com
Despite immense progress in antiretroviral therapy (ART) scale-up, many people still lack
access to basic standards of care, with our ability to meet the Joint United Nations …

Monitoring and switching of first-line antiretroviral therapy in adult treatment cohorts in sub-Saharan Africa: collaborative analysis

AD Haas, O Keiser, E Balestre, S Brown… - The lancet HIV, 2015 - thelancet.com
Background HIV-1 viral load testing is recommended to monitor antiretroviral therapy (ART)
but is not universally available. The aim of our study was to assess monitoring of first-line …

The need for second-line antiretroviral therapy in adults in sub-Saharan Africa up to 2030: a mathematical modelling study

J Estill, N Ford, L Salazar-Vizcaya, AD Haas… - The Lancet …, 2016 - thelancet.com
Background The number of patients in need of second-line antiretroviral drugs is increasing
in sub-Saharan Africa. We aimed to project the need of second-line antiretroviral therapy in …

Point-of-care and near real-time testing for antiretroviral adherence monitoring to HIV treatment and prevention

PK Drain, AR Bardon, JM Simoni, TR Cressey… - Current HIV/AIDS …, 2020 - Springer
Abstract Purpose of Review In this report, we review the need for point-of-care (POC) or near
real-time testing for antiretrovirals, progress in the field, evidence for guiding implementation …

Early antiretroviral therapy initiation: access and equity of viral load testing for HIV treatment monitoring

T Peter, D Ellenberger, AA Kim, D Boeras… - The Lancet Infectious …, 2017 - thelancet.com
Scaling up access to HIV viral load testing for individuals undergoing antiretroviral therapy in
low-resource settings is a global health priority, as emphasised by research showing the …

Developments in CD4 and viral load monitoring in resource-limited settings

CF Rowley - Clinical infectious diseases, 2014 - academic.oup.com
CD4 counts and human immunodeficiency virus (HIV) load testing are essential components
of HIV care, and making these tests available in resource-limited settings is critical to the roll …

The clinical and economic impact of point-of-care CD4 testing in Mozambique and other resource-limited settings: a cost-effectiveness analysis

EP Hyle, IV Jani, J Lehe, AE Su, R Wood… - PLoS …, 2014 - journals.plos.org
Background Point-of-care CD4 tests at HIV diagnosis could improve linkage to care in
resource-limited settings. Our objective is to evaluate the clinical and economic impact of …

Clinical effect and cost-effectiveness of incorporation of point-of-care assays into early infant HIV diagnosis programmes in Zimbabwe: a modelling study

SC Frank, J Cohn, L Dunning, E Sacks… - The lancet HIV, 2019 - thelancet.com
Background New point-of-care (POC) assays for early infant HIV diagnosis are costlier than
conventional total nucleic acid assays, but could increase access to testing, shorten time to …