Cerebral amyloid angiopathy (CAA) is an important cerebral small vessel disease
associated with brain haemorrhage and cognitive change. The commonest form, sporadic …

Cataract is the leading cause of blindness worldwide. Cataract phacoemulsification
combined with intraocular lens implantation causes great burden to global healthcare …

This comprehensive review investigates the pivotal role of reactive oxygen species (ROS) in
cataract formation and evaluates the potential of antioxidant therapies in mitigating this …

This review examines the role of impaired amyloid-β clearance in the accumulation of
amyloid-β in the brain and the periphery, which is closely associated with Alzheimer's …

Understanding neurodegenerative diseases have challenged scientists for decades. It has
become apparent that a decrease in life span is often correlated with the development of …

Background: The aim of this study was to investigate the relationship between serum
cystatin C levels and the presence and severity of cerebral small vessel disease (CSVD) …

Hereditary cystatin C amyloid angiopathy (HCCAA) is an Icelandic disease that belongs to a
disease class called cerebral amyloid angiopathy, a group of heterogenous diseases …

The conversion of human proteins into the highly ordered fibrillar aggregates known as
amyloid fibrils is implicated in a wide range of diseases. The number of proteins known to …

Arfgeng heilablæðing (Hereditary Cystatin C Amyloid Angiopathy, HCCAA) er séríslenskur
ríkjandi sjúkdómur sem erfist óháð kyni. Stökkbreyting á sér í CST3 geninu sem veldur því …

This research builds on the results of previous phase IIa clinical trials conducted by Arctic
Therapeutics. The outcome from that trial was favorable and suggests that N-Acetyl Cysteine …