Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …

The human intestinal tract harbors a profound variety of microorganisms that live in
symbiosis with the host and each other. It is a complex and highly dynamic environment …

Invasive bacteria colonise their host tissues by establishing niches inside eukaryotic cells,
where they grow either in the cytosol or inside a specialised vacuole. These two distinct …

The surge in inflammatory bowel diseases, like Crohn's disease (CD), is alarming. While the
role of the gut microbiome in CD development is unresolved, the frequent isolation of …

Mucosal enrichment of the Adherent-Invasive E. coli (AIEC) pathotype and the expansion of
pathogenic IFNγ-producing Th17 (pTh17) cells have been linked to Crohn's Disease (CD) …

Enteric bacterial infections contribute substantially to global disease burden and mortality,
particularly in the developing world. In vitro 2D monolayer cultures have provided critical …

Inflammatory bowel disease (IBD)-associated fibrosis causes significant morbidity.
Mechanisms are poorly understood but implicate the microbiota, especially adherent …

Gut microbiota imbalances play an important role in inflammatory bowel disease (IBD), but
no single pathogenic microorganism critical to IBD that is specific to the IBD terminal ileum …

The central role of the gut microbiota in the regulation of health and disease has been
convincingly demonstrated. Polymicrobial interkingdom interactions between bacterial (the …

Escherichia coli is one of the most common members of the intestinal microbiota. Many of its
strains are associated with various inflammatory infections, including urinary or gut …