Niosome as an effective nanoscale solution for the treatment of microbial infections

M Barani, F Paknia, M Roostaee… - BioMed Research …, 2023 - Wiley Online Library
Numerous disorders go untreated owing to a lack of a suitable drug delivery technology or
an appropriate therapeutic moiety, particularly when toxicities and side effects are a major …

Nano-mediated strategy for targeting and treatment of non-small cell lung cancer (NSCLC)

S Ashique, A Garg, N Mishra, N Raina, LC Ming… - Naunyn-Schmiedeberg's …, 2023 - Springer
Lung cancer is the most common type of cancer, with over 2.1 million cases diagnosed
annually worldwide. It has a high incidence and mortality rate, leading to extensive research …

Nintedanib in idiopathic pulmonary fibrosis: tolerability and safety in a real life experience in a single centre in patients also treated with oral anticoagulant therapy

B Ruaro, I Gandin, R Pozzan, S Tavano, C Bozzi… - Pharmaceuticals, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a rare and severe disease with a median survival of~ 3
years. Nintedanib (NTD) has been shown to be useful in controlling interstitial lung disease …

A Nanoemulgel for Nose-to-Brain delivery of Quetiapine–QbD-Enabled formulation development & in-vitro characterization

D Gadhave, M Quadros, AR Ugale, M Goyal… - International Journal of …, 2023 - Elsevier
Second-generation antipsychotics, quetiapine hemifumarate (QF), exhibited highly active
against negative and positive signs of psychosis. However, contemporary reports have …

Development and characterization of inhaled nintedanib-loaded PLGA nanoparticles using scalable high-pressure homogenization technique

X Wang, D Gadhave, G Chauhan, V Gupta - Journal of Drug Delivery …, 2024 - Elsevier
Presently, non-invasive targeted drug delivery to the lungs represents a routinely
investigated approach to treat challenging disorders such as pulmonary fibrosis. Nintedanib …

Investigation on the structural and dynamical properties of cationic, anionic, and catanionic niosomes as multifunctional controlled drug delivery system for …

A Poustforoosh - Colloids and Surfaces A: Physicochemical and …, 2024 - Elsevier
Background Niosomes are versatile nanocarriers for therapeutic compounds, and optimizing
their structures via ionic surfactants can enhance their functionality considerably. Catanionic …

Niosomes: Composition, Formulation Techniques, and Recent Progress as Delivery Systems in Cancer Therapy

S Liga, C Paul, EA Moacă, F Péter - Pharmaceutics, 2024 - mdpi.com
Niosomes are vesicular nanocarriers, biodegradable, relatively non-toxic, stable, and
inexpensive, that provide an alternative for lipid-solid carriers (eg, liposomes). Niosomes …

Advanced delivery strategies of nintedanib for lung disorders and beyond: A comprehensive review

D Thakkar, S Singh, S Wairkar - AAPS PharmSciTech, 2024 - Springer
Nintedanib, a primary treatment for lung fibrosis, has gathered substantial attention due to its
multifaceted potential. A tyrosine kinase inhibitor, nintedanib, inhibits multiple signalling …

Inhalable dry powder containing lipid polymer hybrid nanoparticles of Nintedanib esylate: In vitro and in vivo evaluations

M Patel, S Karampuri, V Kansara, B Vyas - Journal of Drug Delivery …, 2023 - Elsevier
The key objective of this research work was to develop and evaluate dry powder for
inhalation containing lipid polymer hybrid nanoparticles (LPHNPs) loaded with Nintedanib …

Nanocarrier-Mediated Drug Delivery via Inhalational Route for Lung Cancer Therapy: A Systematic and Updated Review

N Ara, A Hafeez - AAPS PharmSciTech, 2024 - Springer
Lung cancer is one of the most severe lethal malignancies, with approximately 1.6 million
deaths every year. Lung cancer can be broadly categorised into small and non-small-cell …