Background Age-associated DNA methylation changes provide a promising biomarker for
the aging process. While genome-wide DNA methylation profiles enable robust age …

Age estimation is a critical aspect of reconstructing a biological profile in forensic sciences.
Diverse biochemical processes have been studied in their correlation with age, and the …

Recent advances in epigenetic research have enabled the development of epigenetic
clocks, which have greatly enhanced our ability to investigate molecular processes that …

Background Epigenome‐wide association studies for cardiometabolic risk factors have
discovered multiple loci associated with incident cardiovascular disease (CVD). However …

Rationale: Smoking results in at least a decade lower life expectancy. Mortality among
current smokers is two to three times as high as never smokers. DNA methylation is an …

Epigenetic dysregulation is involved in a wide spectrum of diseases, and many studies have
reported differential molecular epigenetic signatures between diseased tissues/cells and …

In view of the sex differences in aging‐related diseases, sex chromosomes may play a
critical role during aging process. This study aimed to identify age‐related DNA methylation …

Background Treatment failure in eosinophilic esophagitis (EoE) is common. We hypothesize
that DNA methylation differs between patients by treatment response to topical steroids (oral …

While earlier first-generation epigenetic aging clocks were trained to estimate chronological
age as accurately as possible, more recent next-generation clocks incorporate DNA …

Background Epigenetic aging signatures can provide insights into the human aging process.
Within the last decade many alternative epigenetic clocks have been described, which are …