Coexistence of blaNDM-1 and blaIMP-4 in One Novel Hybrid Plasmid Confers Transferable Carbapenem Resistance in an ST20-K28 Klebsiella pneumoniae

X Jia, P Jia, Y Zhu, W Yu, X Li, J Xi, X Liu… - Frontiers in …, 2022 - frontiersin.org
Objectives We identified a novel hybrid plasmid simultaneously carrying bla NDM-1 and bla
IMP-4 in an ST20-K28 carbapenem-resistant Klebsiella pneumoniae (CRKP) strain AZS099 …

[HTML][HTML] Genomic insight into the distribution and genetic environment of blaIMP-4 in clinical carbapenem-resistant Klebsiella pneumoniae strains in China

Z Zheng, L Liu, L Ye, Y Xu, S Chen - Microbiological Research, 2023 - Elsevier
Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a major threat to public health
due to its resistance to almost all antibiotics. It is associated with substantial morbidity and …

Coexistence of a novel NDM-1-encoding MDR plasmid and an IMP-4-encoding IncN-IncU hybrid plasmid in a clinical isolate of Citrobacter freundii BC73

N Liu, B Tang, H Wang, X Chen, P Wen… - Frontiers in …, 2024 - frontiersin.org
Objectives To investigate the genetic characteristics and transmission mechanism of the
NDM-1-, IMP-4-, and SHV-12-producing multidrug-resistant (MDR) clinical isolate …

Emergence of Carbapenem-Resistant ST244, ST292, and ST2446 Pseudomonas aeruginosa Clones in Burn Patients in Yunnan Province

Y Fang, Z Baloch, W Zhang, Y Hu, R Zheng… - Infection and drug …, 2022 - Taylor & Francis
Introduction The prevalence of carbapenem-resistant Pseudomonas aeruginosa is
increasing persistently, particularly in burn ward isolates. Here, we investigate the …

Molecular characteristics of global β-lactamase-producing Enterobacter cloacae by genomic analysis

J Hu, J Li, C Liu, Y Zhang, H Xie, C Li, H Shen, X Cao - Bmc Microbiology, 2022 - Springer
Objective To analyze the characteristics of global β-lactamase-producing Enterobacter
cloacae including the distribution of β-lactamase, sequence types (STs) as well as plasmid …

Antimicrobial resistance and mechanisms of azithromycin resistance in nontyphoidal Salmonella isolates in Taiwan, 2017 to 2018

CS Chiou, YP Hong, YW Wang, BH Chen… - Microbiology …, 2023 - Am Soc Microbiol
Antimicrobial resistance was investigated in 2,341 nontyphoidal Salmonella (NTS) isolates
recovered from humans in Taiwan from 2017 to 2018 using antimicrobial susceptibility …

Molecular characteristics of clinical IMP-producing Klebsiella pneumoniae isolates: novel IMP-90 and integron In2147

L Yang, G Zhang, Q Zhao, L Guo, J Yang - Annals of Clinical Microbiology …, 2023 - Springer
Background Since the first report of carbapenem-resistant Klebsiella pneumoniae isolates in
China in 2007, the prevalence of CRKP and CRE has increased significantly. However, the …

Phenotypic and genomic characteristics of clinical IMP-producing Klebsiella spp. Isolates in China

C Liu, N Dong, Y Zhang, Q Sun, Y Huang… - Communications …, 2024 - nature.com
Background IMP-producing Klebsiella spp.(IMPKsp) strains have spread globally, including
in China. Currently, the prevalence and genomic characterization of IMPKsp is largely …

First Report of blaIMP–4 and blaSRT–2 Coproducing Serratia marcescens Clinical Isolate in China

X Huang, S Shen, Q Shi, L Ding, S Wu, R Han… - Frontiers in …, 2021 - frontiersin.org
Carbapenem-resistant Enterobacterales (CRE) has become a major therapeutic concern in
clinical settings, and carbapenemase genes have been widely reported in various bacteria …

Characterization of a Conjugative Hybrid Plasmid Coharboring blaKPC-2 and blaIMP-4 in a Klebsiella quasipneumoniae Clinical Isolate

H Dong, Z Liu, Z Wu, T Zhang, Z Xia, Y Zhao… - Microbiology …, 2023 - Am Soc Microbiol
Generation of hybrid MDR plasmids accelerated the evolution and transmission of
resistance genes. In this study, we characterized a bla KPC-2-and bla IMP-4-coharboring …