Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review
B Peltanova, M Raudenska, M Masarik - Molecular cancer, 2019 - Springer
The tumor microenvironment (TME) is comprised of many different cell populations, such as
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …
cancer-associated fibroblasts and various infiltrating immune cells, and non-cell …
Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …
Cancer-associated fibroblasts in oral cancer: a current perspective on function and potential for therapeutic targeting
The role of the tumour microenvironement (TME) in cancer progression and resistance to
therapies is now widely recognized. The most prominent non-immune cell type in the …
therapies is now widely recognized. The most prominent non-immune cell type in the …
Mutual concessions and compromises between stromal cells and cancer cells: driving tumor development and drug resistance
Background Various cancers have been found to be associated with heterogeneous and
adaptive tumor microenvironments (TMEs) and to be driven by the local TMEs in which they …
adaptive tumor microenvironments (TMEs) and to be driven by the local TMEs in which they …
The immune cells in the development of oral squamous cell carcinoma
Simple Summary The cells of the immune system can exert a dual effect on cancer
development and growth. On the one hand, the immune system can be activated by tumor …
development and growth. On the one hand, the immune system can be activated by tumor …
The 'danse macabre'—neutrophils the interactive partner affecting oral cancer outcomes
S Hadjigol, BA Shah, NM O'Brien-Simpson - Frontiers in Immunology, 2022 - frontiersin.org
Over the past few decades, tremendous advances in the prevention, diagnosis, and
treatment of cancer have taken place. However for head and neck cancers, including oral …
treatment of cancer have taken place. However for head and neck cancers, including oral …
Distribution and significance of interstitial fibrosis and stroma-infiltrating B cells in tongue squamous cell carcinoma
XM Lao, YJ Liang, YX Su, SE Zhang… - Oncology …, 2016 - spandidos-publications.com
Inflammation and desmoplasia are frequently identified in the tumor microenvironment, and
have been demonstrated to be effective modulators of malignant biological events …
have been demonstrated to be effective modulators of malignant biological events …
GLUT-1 immunoexpression in oral epithelial dysplasia, oral squamous cell carcinoma, and verrucous carcinoma
VC Angadi, PV Angadi - Journal of oral science, 2015 - jstage.jst.go.jp
Glucose transporters, such as GLUT-1, mediate the important mechanisms involved in
cellular glucose influx, allowing cells to proliferate and survive. The significance of GLUT-1 …
cellular glucose influx, allowing cells to proliferate and survive. The significance of GLUT-1 …
Fibroblast activation and senescence in oral cancer
There is now compelling evidence that the tumour stroma plays an important role in the
pathogenesis of cancers of epithelial origin. The pre‐eminent cell type of the stroma is …
pathogenesis of cancers of epithelial origin. The pre‐eminent cell type of the stroma is …
Ki67, CD105 and α‐smooth muscle actin expression in disease progression model of oral submucous fibrosis
Aim The aim of this study was to investigate the expression of Ki67, CD105 and α‐smooth
muscle actin (α‐SMA) expression in oral submucous fibrosis (OSF) and oral squamous cell …
muscle actin (α‐SMA) expression in oral submucous fibrosis (OSF) and oral squamous cell …