This paper summarizes recent developments in the synthesis, application and mechanistic
studies on polysaccharide-based chiral stationary phases (CSPs) for liquid phase …

This paper reviews analytical approaches published in 2002–2012 for chiral drug analysis
and their relevance in research and practice in the field of clinical and forensic toxicology …

Delineating its usage in separation, purification and detection processes across a variety of
disciplines, from industry to applied research, this work discusses the principles, techniques …

Three eco-friendly spectrophotometric methods were developed for determination of the
novel anticoagulant drug, betrixaban (BTX). The first method (method A) was based on …

The goal of this study was to compare the performance of three separation techniques for
the analysis of 57 hydrophilic compounds. RPLC, hydrophilic interaction liquid …

The characterization of the drug metabolism and pharmacokinetic (DMPK) profiles of
stereoisomers is a fundamental aspect of the drug discovery and development processes …

An analysis of recent trends indicates that CE can show real advantages over
chromatographic methods in ultratrace enantioselective determination of biologically active …

In this work, we compared APPI and APCI for normal-phase LC/MS chiral analysis of five
pharmaceuticals. Performance was compared both by FIA and by on-column analysis using …

A sensitive and specific liquid chromatography-tandem mass spectrometric method has
been developed and validated for the quantification of the five 1, 4-dihydropyridine calcium …

In the present study, carboxymethylchitosan (CMCS) was prepared from chitosan,
crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for site specific …