Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …

Neuroinflammation is initiated with an aberrant innate immune response in the central
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …

Inflammasome is a cytoplasmic multiprotein complex that facilitates the clearance of
exogenous microorganisms or the recognition of endogenous danger signals, which is …

Pathogen-associated molecular patterns (PAMPs) and danger-associated molecular
patterns (DAMPs) induce NLRP3 inflammasome activation, and subsequent formation of …

There is increasing evidence that exosome-mediated transmission of microRNAs helps to
connect tumor-associated macrophages and cancer cells, including lung adenocarcinoma …

The NLRP3 inflammasome plays an important role in protecting the host from infection and
aseptic inflammation, and its regulatory mechanism is not completely understood …

The food industry has been focusing on food bioactive compounds with multiple
physiological and immunological properties that benefit human health. These bioactive …

The cytoplasmic oligomer NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome
has been implicated in most inflammatory and autoimmune diseases. Here, we highlight the …

Objectives:. Asthma is a highly heterogeneous disease, and T-helper cell type 17 (Th17)
cells play a pathogenic role in the development of non-T2 severe asthma. Misshapen like …

NLRP3 is a prototypical sensor protein connecting cellular stress to pro-inflammatory
signaling. A complex array of regulatory steps is required to switch NLRP3 from an inactive …