The management of primary CNS lymphoma is one of the most controversial topics in neuro-
oncology because of the complexity of the disease and the very few controlled studies …

The management of primary central nervous system (PCNSL) is one of the most
controversial topics in neuro-oncology because of the complexity of the disease and the …

Summary Background The International Extranodal Lymphoma Study Group-32 (IELSG32)
trial is an international randomised phase 2 study that addresses two key clinical questions …

Purpose A multicenter phase II study was conducted to assess the efficacy of rituximab,
methotrexate, procarbazine, and vincristine (R-MPV) followed by consolidation reduced …

Objective Real-life studies on patients with primary CNS lymphoma (PCNSL) are scarce.
Our objective was to analyze, in a nationwide population-based study, the current medical …

Background Chemotherapy with high-dose methotrexate is the conventional approach to
treat primary CNS lymphomas, but superiority of polychemotherapy compared with high …

Purpose: To identify survival predictors and to design a prognostic score useful for
distinguishing risk groups in immunocompetent patients with primary CNS lymphomas …

Primary central nervous system lymphoma (PCNSL) is a rare form of non-Hodgkin
lymphoma that affects the brain parenchyma, spinal cord, eyes, and cerebrospinal fluid …

The article offers guidelines for the diagnosis and management of primary central nervous
system diffuse large B-cell lymphoma. It informs on symptoms associated with the disease …

Folate-mediated one carbon (1C) metabolism supports a series of processes that are
essential for the cell. Through a number of interlinked reactions happening in the cytosol …