A review on the modernization of pharmaceutical development and manufacturing–Trends, perspectives, and the role of mathematical modeling

F Destro, M Barolo - International Journal of Pharmaceutics, 2022 - Elsevier
Recently, the pharmaceutical industry has been facing several challenges associated to the
use of outdated development and manufacturing technologies. The return on investment on …

[HTML][HTML] Maximizing information from chemical engineering data sets: Applications to machine learning

A Thebelt, J Wiebe, J Kronqvist, C Tsay… - Chemical Engineering …, 2022 - Elsevier
It is well-documented how artificial intelligence can have (and already is having) a big
impact on chemical engineering. But classical machine learning approaches may be weak …

Perspectives on nonstationary process monitoring in the era of industrial artificial intelligence

C Zhao - Journal of Process Control, 2022 - Elsevier
The development of the Internet of Things, cloud computing, and artificial intelligence has
given birth to industrial artificial intelligence (IAI) technology, which enables us to obtain fine …

Performance supervised plant-wide process monitoring in industry 4.0: A roadmap

Y Jiang, S Yin, O Kaynak - IEEE Open Journal of the Industrial …, 2020 - ieeexplore.ieee.org
The intensive research and development efforts directed towards large-scale complex
industrial systems in the context of Industry 4.0 indicate that safety and reliability issues pose …

MoniNet with concurrent analytics of temporal and spatial information for fault detection in industrial processes

W Yu, C Zhao, B Huang - IEEE Transactions on Cybernetics, 2021 - ieeexplore.ieee.org
Modern industrial plants generally consist of multiple manufacturing units, and the local
correlation within each unit can be used to effectively alleviate the effect of spurious …

A review on data-driven process monitoring methods: Characterization and mining of industrial data

C Ji, W Sun - Processes, 2022 - mdpi.com
Safe and stable operation plays an important role in the chemical industry. Fault detection
and diagnosis (FDD) make it possible to identify abnormal process deviations early and …

A review of kernel methods for feature extraction in nonlinear process monitoring

KE Pilario, M Shafiee, Y Cao, L Lao, SH Yang - Processes, 2019 - mdpi.com
Kernel methods are a class of learning machines for the fast recognition of nonlinear
patterns in any data set. In this paper, the applications of kernel methods for feature …

A new key performance indicator oriented industrial process monitoring and operating performance assessment method based on improved Hessian locally linear …

H Zhang, C Zhang, J Dong, K Peng - International Journal of …, 2022 - Taylor & Francis
The industrial process monitoring and operating performance assessment techniques are of
great significance to ensure the safety and efficiency of the production and to improve the …

Local–global modeling and distributed computing framework for nonlinear plant-wide process monitoring with industrial big data

Q Jiang, S Yan, H Cheng, X Yan - IEEE transactions on neural …, 2020 - ieeexplore.ieee.org
Industrial big data and complex process nonlinearity have introduced new challenges in
plant-wide process monitoring. This article proposes a local-global modeling and distributed …

Robust and sparse canonical correlation analysis for fault detection and diagnosis using training data with outliers

L Luo, W Wang, S Bao, X Peng, Y Peng - Expert Systems with Applications, 2024 - Elsevier
A well-known shortcoming of the traditional canonical correlation analysis (CCA) is the lack
of robustness against outliers. This shortcoming hinders the application of CCA in the case …